anti-DLC1 Antibody
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Catalog number30-796
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PricePlease ask
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Size50 ug
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Gene infoThis gene is deleted in the primary tumor of hepatocellular carcinoma. It maps to 8p22-p21.3, a region frequently deleted in solid tumors. It is suggested that this gene is a candidate tumor suppressor gene for human liver cancer, as well as for prostate, lung, colorectal, and breast cancers. DLC1 functions as a GTPase-activating protein specific for Rho and an activator of PLCD1 in vivo and induces morphological changes and detachment through cytoskeletal reorganization.
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Gene namesDLC1, ARHGAP7, FLJ21120, HP, STARD12, p122-RhoGAP
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Antibodie s labelunlabelled serum
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PurityAntibody is purified by peptide affinity chromatography method.
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Ab raised inRabbit
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TypePolyclonal
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AntigenAntibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DLC1.
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Immuno applicationELISA, Western Blot
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Antibody adviceDLC1 antibody can be used for detection of DLC1 by ELISA at 1:12500. DLC1 antibody can be used for detection of DLC1 by western blot at 0.5 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
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Suspention pH azideAntibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
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Keep atFor short periods of storage (days) store at 4 grades C. For longer periods of storage, store DLC1 antibody at -20 grades C. As with any antibody avoid repeat freeze-thaw cycles.
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Works withHuman, Mouse, Rat
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Omim nr119584256
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Ncbi nrEAW63852
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KDa52 kDa
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Vial with antibodyLyophilized
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Quantity per ml1 mg/ml
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NCBI GENE nr10395
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GENE symbolDLC1
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Antigene namedeleted in liver cancer 1
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SourceHomo sapiens
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Protein nrQ9Y238
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolDLEC1, DYNLL1, DLC1
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Short nameanti-DLC1 Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toDLC1 (antibody to-)
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Alternative techniqueantibodies
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Alternative to gene targetdeleted in liver cancer 1, ARHGAP7 and HP and p122-RhoGAP and STARD12, DLC1 and IDBG-7954 and ENSG00000164741 and 10395, SH2 domain binding, nuclei, Dlc1 and IDBG-149173 and ENSMUSG00000031523 and 50768, BT.24236 and IDBG-628726 and ENSBTAG00000015541 and 511433
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Gene info
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Identity
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Gene
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Long gene nameDLEC1 cilia and flagella associated protein
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Synonyms gene name
- deleted in lung and esophageal cancer 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1999-05-07
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Cilia and flagella associated
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namedynein light chain LC8-type 1
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Synonyms gene
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Synonyms gene name
- dynein, cytoplasmic, light polypeptide 1
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Synonyms
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GenBank acession
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Locus
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Discovery year2002-12-18
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Dyneins, axonemal inner arm I1/f complex subunits
- Dynein 2 complex subunits
- Dynein 1 complex subunits
- Dyneins, axonemal outer arm complex subunits
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameDLC1 Rho GTPase activating protein
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Synonyms gene name
- deleted in liver cancer 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1999-06-17
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- StAR related lipid transfer domain containing
- Rho GTPase activating proteins
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data