anti-TWEAK Antibody
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Catalog number3791
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PricePlease ask
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Size0.02 mg, 0.1 mg
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Gene infoTWEAK Antibody: TNF-related weak inducer of apoptosis (TWEAK) is a member of the tumor necrosis factor superfamily (TNFSF) of structurally related cytokines. Like most other members of this family, TWEAK is a cell surface-associated type II transmembrane protein although a smaller, biologically active form can also be generated by cleavage near the cell membrane. TWEAK has multiple biological activities, including stimulation of cell growth and angiogenesis, induction of inflammatory cytokines, in addition to stimulation of apoptosis. The TWEAK signal transduction pathway has not been well established but it appears to signal via TweakR/Fn14 in a manner similar to that described for other TNFSF members that bind receptors lacking death domains.
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Gene namesTWEAK Antibody: APO3L, DR3LG, TWEAK, APO3L, UNQ181/PRO207, Tumor necrosis factor ligand superfamily member 12, APO3 ligand
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Antibodie s labelunlabelled serum
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PurityTWEAK Antibody is Protein A-purified.
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Ab raised inRabbit
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TypePolyclonal
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ImmunoglobulinIgG
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AntigenTWEAK antibody was made against recombinant human TWEAK protein.
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Immuno applicationELISA, Western Blot, immuno-histo-chemistry
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Antibody adviceTWEAK antibody can be used for the detection of TWEAK by Western blot at 1 ug/mL. Antibody can also be used for immunohistochemistry starting at 10 ug/mL.
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Suspention pH azideTWEAK Antibody is supplied in PBS containing 0.02% sodium azide.
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Keep atTWEAK antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Works withHuman, Mouse, Rat
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Omim nr4507597
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Ncbi nrNP_003800
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KDaPredicted: 27 kDa
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Vial with antibodyin solution
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Quantity per ml1 mg/mL
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NCBI GENE nr8742
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GENE symbolTNFSF12
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Antigene nametumor necrosis factor (ligand) superfamily, member 12
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SourceHomo sapiens
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Protein nrO43508
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolTNFSF12
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Short nameanti-TWEAK Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toTWEAK (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameTNF superfamily member 12
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Synonyms gene name
- tumor necrosis factor (ligand) superfamily, member 12
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-12-04
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Tumor necrosis factor superfamily
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data