Anti-DNCLI1 (Polyclonal), ALEXA Fluor 555

  • Catalog number
    GENTObs-20152R-A555
  • Price
    Please ask
  • Size
    100 microliters
  • Type
    Conjugated Primary Antibody
  • Conjugated with
    ALEXA FLUOR® 555
  • Host organism
    Rabbit (Oryctolagus cuniculus)
  • Target Protein Peptide
    DNCLI1
  • Specificity
    This antibody reacts specifically with DNCLI1 ALEXA FLUOR® 555
  • Modification
    No modification has been applied to this antibody
  • Modification site
    None
  • Clonality
    Polyclonal Antibody
  • Clone
    Polyclonal Antibodies
  • Concentration
    1ug per 1ul
  • Subcellular locations
    Cytoplasm
  • Antigen Source
    KLH conjugated synthetic peptide derived from human DNCLI1
  • Gene ID
    51143
  • Swiss Prot
    Q9Y6G9
  • Applications
    IF(IHC-P)
  • Applications with corresponding dilutions
    IF(IHC-P)(1:50-200)
  • Cross reactive species
    Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
  • Cross Reactive Species details
    No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
  • Background information
    Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. Probably involved in the microtubule-dependent transport of pericentrin. Is required for progress throuh the spindle assembly checkpoint. The phosphorylated form appears to be involved in the selective removal of MAD1L1 and MAD1L2 but not BUB1B from kinetochores.
  • Purification method
    Purified by Protein A.
  • Storage
    Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
  • Excitation emission
    553nm/568nm
  • Synonyms
    LIC1; DNCLI1; Cytoplasmic dynein 1 light intermediate chain 1; Dynein light chain A; DLC-A; Dynein light intermediate chain 1, cytosolic; DYNC1LI1
  • Also known as
    DNCLI1 Polyclonal Antibody ALEXA FLUOR® 555
  • Other name
    Anti-DNCLI1 Polyclonal ALEXA FLUOR® 555
  • Advisory
    Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
  • Properties
    For facs or microscopy Alexa 1 conjugate. Very high photo stable ALEXA conjugate.
  • Conjugation
    Alexa Fluor, ALEXA FLUOR 555
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
  • Group
    Polyclonals and antibodies
  • About
    Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
  • Gene target
    DNCLI1  
  • Gene symbol
    DYNC1LI1
  • Short name
    Anti-DNCLI1 ALEXA FLUOR® 555
  • Technique
    Polyclonal, anti-, anti, antibody to, antibodies, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
  • Isotype
    Immunoglobulin G (IgG)
  • Label
    ALEXA FLUOR 555
  • Alternative name
    DNCLI1 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated
  • Alternative technique
    polyclonals, antibodies
Gene info
  • Identity
  • Gene
  • Long gene name
    dynein cytoplasmic 1 light intermediate chain 1
  • Synonyms gene
  • Synonyms gene name
    • dynein, cytoplasmic, light intermediate polypeptide 1
  • GenBank acession
  • Locus
  • Discovery year
    2002-06-12
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Dynein 1 complex subunits
  • VEGA ID
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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