anti-Disp2 Antibody

  • Catalog number
    4883
  • Price
    Please ask
  • Size
    0.02 mg, 0.1 mg
  • Gene info
    Disp2 Antibody: Disp2 is the second of three known homologs of the D. melanogaster protein Dispatched. It is a multi-transmembrane protein containing two PTCH/DISP domains and is thought to be involved in the release of lipid-anchored Hedgehog from producing cells. Hedgehog is a major player in signaling pathways during embryogenesis, tissue regeneration, and carcinogenesis and the Disp proteins have been implicated in these pathways. Recently, it has been shown that Disp2 is translationally regulated by the microRNA miR-214 in zebrafish. Expression of this miRNA decreased Disp2 promoter activity in vitro and its overexpression in zebrafish resulted in a phenotype identical to that observed by Disp2 mutants. At least two isoforms of Disp2 are known to exist. This Disp2 antibody is predicted to not cross-react with Disp1 or Disp3.
  • Gene names
    Disp2 Antibody: DISPB, HsT16908, DISPB, KIAA1742, Protein dispatched homolog 2
  • Antibodie s label
    unlabelled serum
  • Purity
    Disp2 Antibody is affinity chromatography purified via peptide column.
  • Ab raised in
    Rabbit
  • Type
    Polyclonal
  • Immunoglobulin
    IgG
  • Antigen
    Disp2 antibody was made against a 19 amino acid synthetic peptide from near the carboxy terminus of human Disp2.
  • Immuno application
    ELISA, Western Blot
  • Antibody advice
    Disp2 antibody can be used for the detection of Disp2 by Western blot at 1 - 2 ug/mL.
  • Suspention pH azide
    Disp2 Antibody is supplied in PBS containing 0.02% sodium azide.
  • Keep at
    Disp2 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Works with
    Human, Mouse, Rat
  • Omim nr
    160380692
  • Ncbi nr
    A7MBM2
  • Vial with antibody
    in solution
  • Quantity per ml
    1 mg/mL
  • NCBI GENE nr
    85455
  • GENE symbol
    DISP2
  • Antigene name
    dispatched homolog 2 (Drosophila)
  • Source
    Homo sapiens
  • Protein nr
    A7MBM2
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
  • Properties
    If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    Disp2  
  • Gene symbol
    DISP2
  • Short name
    anti-Disp2 Antibody
  • Technique
    Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
  • Alternative name
    Antibody toDisp2 (antibody to-)
  • Alternative technique
    antibodies
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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