anti-DFF40 Antibody

anti-DFF40 Antibody is available 1 time from Biovision labs

3049-100 | anti-DFF40 Antibodysize: DFF40 Antibody | 391.67 USD

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  • Target of this antibody:
    DFF40
  • Alternative names of antibody target:
    DFFB, CAD, DFF-40 , CPAN , DFF2
  • Background information:
    DFF is composed of two subunits: DFF40/CAD and DFF45/ICAD. Human DFF45 and its mouse homologue ICAD are the inhibitors of DFF40 and CAD, respectively. Cleavage of DFF45, which is mediated by caspase-3, leads to DFF40’s activation as a nuclease. Activation of DFF40/CAD can lead to DNA fragmentation, a hallmark of apoptosis. DFF40 mRNA is expressed in limited number of human tissues: pancreas, spleen, prostate, and ovary.
  • Antibody host:
    Rabbit
  • Clonality of antibody:
    Polyclonal
  • Isotype:
    Rabbit IgG
  • This antibody reacts with:
    Human, mouse, rat
  • Immunogene sequence:
    Synthetic peptide surrounding amino acid 208 of mouse DFF40
  • Concentration of antibody:
    0.2 mg/ml
  • Form of antibody:
    Liquid
  • Formulation of this antibody:
    100 µg (0.2 mg/ml) immunoaffinity purified rabbit DFF40 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
  • Purification method:
    Affinity purified
  • This antibody has been succesfully tested for use in following methods:
    Western blot
  • Recommended usage:
    Western blotting (0.5-4 µg/ml) and Immunohistochemistry (2-8 µg/ml). However, the optimal conditions should be determined individually. The antibody detects a 43 kDa DFF40/CAD of human, mouse and rat origins. Mouse kidney tissue lysate can be used as a positive control.
  • Storage information:
    Shelf time: 12 months in temp.: -20 deg.C
  • Shipping conditions:
    gel pack
  • How to handle this antibody:
    The antibody solution should be gently mixed before use.
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
  • Properties
    If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
  • Short name
    anti-DFF40 Antibody
  • Technique
    Antibody, anti
  • Alternative name
    antibody to-DFF40 (Antibody to)
  • Alternative technique
    antibodies
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