anti-DEPTOR Antibody

• Catalog number
  7787
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  DEPTOR is an mTOR (mammalian target of rapamycin)-interacting protein whose expression is negatively regualted by mTOR complex 1 (mTORC1) and mTORC2 (1). Loss of DEPTOR activates RP6SK1, Akt1, and SGK1, promotes cell growth and survival, and activates mTORC1 and mTORC2 kinase activities. DEPTOR expression is low in most cancers, but is often elevated in multiple myelomas (1). In respons to stimulation by mitogens, DEPTOR is rapidly phosphorylated leading to its ubiquitination and degradation, allowing mTOR to generate an auto-amplification loop to promotes its own full activation (2).
• Gene names
  DEPTOR Antibody: DEP.6, DEPDC6, DEP domain-containing mTOR-interacting protein, DEP domain-containing protein 6
• Antibodie s label
  unlabelled serum
• Purity
  DEPTOR antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Spicific to
  DEPTOR antibody is human, mouse and rat reactive. At least three isoforms of DEPTOR are known to exist; this antibody will detect all three isoforms.
• Antigen
  DEPTOR antibody was made against a 16 amino acid peptide near the center of human DEPTOR.
• Immuno application
  ELISA, Western Blot, immuno-histo-chemistry
• Antibody advice
  DEPTOR antibody can be used for detection of DEPTOR by Western blot at 1 - 2 ug/ml. Antibody can also be used for Immunohistochemistry at 5 ug/mL.
• Suspention pH azide
  DEPTOR Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  DEPTOR antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year.
• Works with
  Human, Mouse, Rat
• Omim nr
  189571664
• Ncbi nr
  NP_073620
• KDa
  Predicted: 45 kDa Observed: 42 kDa
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  64798
• GENE symbol
  DEPTOR
• Antigene name
  DEP domain containing MTOR-interacting protein
• Source
  homo sapiens
• Protein nr
  Q8TB45
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  DEPTOR  
• Gene symbol
  DEPTOR-AS1, DEPTOR
• Short name
  anti-DEPTOR Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toDEP domain containing Mammalian target on rapamycin-interacting protein (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  DEP domain containing MTOR-interacting protein, DEPTOR and IDBG-34051 and ENSG00000155792 and 64798, protein binding, multiple, Deptor and IDBG-141160 and ENSMUSG00000022419 and 97998, BT.28648 and IDBG-645663 and ENSBTAG00000015341 and 617606

Gene info

• Identity
  HGNC:55602
• Gene
  DEPTOR-AS1
• Long gene name
  DEPTOR antisense RNA 1
• Locus
  8q24.12
• Discovery year
  2021-06-07
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:22953
• Gene
  DEPTOR
• Long gene name
  DEP domain containing MTOR interacting protein
• Synonyms gene
  • DEPDC6
• Synonyms gene name
  • DEP domain containing 6
• Synonyms
  • DEP.6
  • FLJ12428
• Locus
  8q24.12
• Discovery year
  2004-02-23
• Entrez gene record
  64798
• Pubmed identfication
  • 19446321
• RefSeq identity
  • NM_022783
• Classification
  • PDZ domain containing
• VEGA ID
  OTTHUMG00000165052

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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