anti-DCLRE1C Antibody
-
Catalog number26-583
-
PricePlease ask
-
Size50 ug
-
-
Gene infoDCLRE1C is a nuclear protein that is involved in V (D)J recombination and DNA repair. The protein has single-strand-specific 5'-3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins when complexed with protein kinase, DNA-activated, catalytic polypeptide. Mutations in this gene cause Athabascan-type severe combined immunodeficiency (SCIDA). This gene encodes a nuclear protein that is involved in V (D)J recombination and DNA repair. The protein has single-strand-specific 5'-3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins when complexed with protein kinase, DNA-activated, catalytic polypeptide. Mutations in this gene cause Athabascan-type severe combined immunodeficiency (SCIDA).
-
Gene namesDCLRE1C, A-SCID, DCLREC1C, FLJ11360, FLJ36438, RS-SCID, SCIDA, SNM1C
-
Antibodie s labelunlabelled serum
-
PurityAntibody is purified by peptide affinity chromatography method.
-
Ab raised inRabbit
-
TypePolyclonal
-
AntigenAntibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DCLRE1C.
-
Immuno applicationELISA, Western Blot
-
Antibody adviceDCLRE1C antibody can be used for detection of DCLRE1C by ELISA at 1:2500. DCLRE1C antibody can be used for detection of DCLRE1C by western blot at 1 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
-
Suspention pH azideAntibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
-
Keep atFor short periods of storage (days) store at 4 grades C. For longer periods of storage, store DCLRE1C antibody at -20 grades C. As with any antibody avoid repeat freeze-thaw cycles.
-
Works withHuman, Rat
-
Omim nr76496499
-
Ncbi nrNP_001029029
-
KDa65 kDa
-
Vial with antibodyLyophilized
-
Quantity per ml1 mg/ml
-
NCBI GENE nr64421
-
GENE symbolDCLRE1C
-
Antigene nameDNA cross-link repair 1C
-
SourceHomo sapiens
-
Protein nrQ96SD1
-
DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
-
PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translationanticorps
-
Gene target
-
Gene symbolDCLRE1C
-
Short nameanti-DCLRE1C Antibody
-
TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
-
Alternative nameAntibody toDNA cross-link repair 1C (antibody to-)
-
Alternative techniqueantibodies
-
Alternative to gene targetDNA cross-link repair 1C, DCLRE1C and IDBG-56338 and ENSG00000152457 and 64421, hydrolase activity, nuclei, Dclre1c and IDBG-133199 and ENSMUSG00000026648 and 227525, DCLRE1C and IDBG-638047 and ENSBTAG00000010220 and 517886
-
Gene info
-
Identity
-
Gene
-
Long gene nameDNA cross-link repair 1C
-
Synonyms gene
-
Synonyms gene name
- severe combined immunodeficiency, type a (Athabascan)
- DNA cross-link repair 1C (PSO2 homolog, S. cerevisiae)
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year2002-01-18
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- DNA cross-link repair family
- MBL fold containing DNA/RNA interacting subfamily
-
VEGA ID
-
Locus Specific Databases
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
