DC-SIGN Antibody, ALEXA FLUOR 594

  • Catalog number
    bs-10053R-A594
  • Price
    Please ask
  • Size
    100ul
  • Long name
    DC-SIGN Polyclonal Antibody, ALEXA FLUOR 594 Conjugated
  • Also known as
    Anti-DC-SIGN PAb ALEXA FLUOR 594
  • Category
    Conjugated Primary Antibodies
  • Conjugated with
    ALEXA FLUOR® 594
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    DC-SIGN
  • Specificity
    This is a highly specific antibody against DC-SIGN.
  • Modification
    Unmodified
  • Modification Site
    None
  • Clonality
    Polyclonal
  • Clone
    Polyclonal antibody
  • Concentration
    1ug per 1ul
  • Subcellular location
    Extracellular
  • Source
    This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DC-SIGN/CD209
  • Gene ID Number
    30835
  • Tested applications
    IF(IHC-P)
  • Recommended dilutions
    IF(IHC-P)(1:50-200)
  • Crossreactivity
    Human
  • Cross reactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the antigen
    Dendritic cells (DCs) that control immune responses were recently found to capture and transport HIV from the mucosal area to remote lymph nodes, where DCs hand over HIV to CD4+ T lymphocytes. DCs also amplify the amount of virus and extend the duration of viral infectivity. Multiple strains of HIV1, HIV2 and SIV bind to DCs via DCSIGN. ICAM3 is the natural ligand for DC-SIGN. A DC-SIGN homologue (termed CD299, DC-SIGNR, L-SIGN and DCSIGN2) was identified recently. DC-SIGN forms a novel gene family with DC-SIGNR and many alternatively spliced isoforms of DC-SIGN and DC-SIGNR. The expression of DC-SIGN was found in mucosal tissues including placenta, small intestine, and rectum.
  • Purification
    Purified by Protein A.
  • Storage conditions
    Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
  • Excitation emission
    590nm/617nm
  • Synonyms
    CLEC4L; Dendritic cell-specic ICAM-3-grabbing non-integrin 1; C type lectin domain family 4 member L; CD 209; CD209; CD209 antigen; CD209 antigen-like protein A; CD209 molecule; Cd209a; CDSIGN; CIRE; DC SIGN1; DCSIGN; Dendritic cell specic ICAM 3 grabbing nonintegrin 1; Dendritic cell specic ICAM3 grabbing nonintegrin 1; Dendritic cell-specic intracellular adhesion molecules ICAM-3 grabbing non-integrin; Dengue fever, protection against, included; Dentritic Cell Specic ICAM3 Grabbing Nonintegrin; HIV GP120 Binding Protein; MGC129965; MGC130443; SIGN-R1; SIGNR5; CD209_HUMAN.
  • Properties
    For facs or microscopy Alexa 1 conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Conjugation
    Alexa Fluor, ALEXA FLUOR® 594
  • Conjugated
    Alexa conjugate 1
  • French translation
    anticorps
  • Gene target
    DC-SIGN  
  • Gene symbol
    CD209, CLEC4M, UBTD2, WFDC21P, TSPAN14, DCSTAMP, DCX, LAMP3, PDCD1LG2, CCL18
  • Short name
    Anti-DC-SIGN
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Isotype
    Immunoglobulin G (IgG)
  • Label
    ALEXA FLUOR 594
  • Alternative name
    DC-SIGN Polyclonal Antibody, ALEXA FLUOR 594
  • Alternative technique
    antibodies
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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