Daxx Antibody
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Catalog number3229-30T
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PricePlease ask
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Size30 µg
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Antibody TargetDaxx
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Target Alternative NameDeath domain-associated protein 6, ETS1-associated protein 1, Fas death domain-associated protein
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Antibody TypePolyclonal
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Species ReactivitiesHuman, mouse, rat
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Immunogen SequenceSynthetic peptide in the middle of the sequence (BV-M28)
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AccessionQ9UER7
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Gene Id1616
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AppearanceColorless liquid
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FormLiquid
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Concentration0.5 mg/ml
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Formulation30 µg (0.5 mg/ml) of antibody in PBS, 0.01 % BSA, 0.01 % thimerosal, and 50 % glycerol, pH 7.2
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PurificationAffinity purified
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ApplicationWestern blot
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Positive ControlWestern blot: Rat Kidneylysate
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Application And UsagesWestern blot: 1:200
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DescriptionApoptosis can be induced by certain cytokines including TNF and Fas ligand through binding to their respective death domain (DD) containing receptors, TNFR1 and Fas. Cell death signals can then be transduced by DD-containing adapter molecules and members of the caspase family. A novel DD-containing adapter molecule was recently cloned from mouse, human and monkey and designated Daxx. Daxx binds to the Fas DD and activates a FADD-independent death pathway that involves the stress activated c-Jun NH2-terminal kinase (JNK). Daxx activates the JNK kinase kinase ASK1 that is also known as MAPKKK5. FADD and Daxx activate two independent pathways downstream of Fas. Daxx mRNA is widely expressed in fetal and adult tissues with the highest amounts being found in the testis.
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Storage Condition-20 °C
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Shipping Conditiongel pack
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Shelf Life12 months
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UsageFor Research Use Only! Not to be used in humans.
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HandlingThe antibody solution should be gently mixed before use.
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Western Blot VerifiedVerified
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Immunocytochemistry VerifiedNot Verified
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Immunofluorescence VerifiedNot Verified
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Immunoprecipitation VerifiedNot Verified
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ELISA VerifiedNot Verified
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ChIP VerifiedNot Verified
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Flow Cytometry VerifiedNot Verified
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PropertiesIf you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolDAXX
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Short nameDaxx Antibody
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit IgG
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Alternative namedeath-domain associated protein (antibody to-)
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Alternative techniqueantibodies
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Alternative to gene targetdeath-domain associated protein, BING2 and DAP6 and EAP1, DAXX and IDBG-82726 and ENSG00000204209 and 102723452,1616, androgen receptor binding, nuclei, Daxx and IDBG-168138 and ENSMUSG00000002307 and 13163, DAXX and IDBG-629026 and ENSBTAG00000016830 and 504336
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Gene info
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Identity
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Gene
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Long gene namedeath domain associated protein
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Synonyms gene name
- death-associated protein 6
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-03-25
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Entrez gene record
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Pubmed identfication
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data