anti-LDL-R Antibody
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Catalog number5163
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PricePlease ask
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Size0.02 mg, 0.1 mg
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Gene infoLDL-R Antibody: The low density lipoprotein receptor (LDL-R) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in the LDL-R gene cause the autosomal dominant disorder, familial hypercholesterolemia. Along with SCARB1, CLDN1, and the tetraspanin superfamily member CD81, LDL-R has been reported to be an entry factor for the Hepatitis C virus. At least three isoforms of LDL-R are known to exist.
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Gene namesLDL-R Antibody: FH, FHC, LDLCQ2, Low-density lipoprotein receptor, LDL receptor
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Antibodie s labelunlabelled serum
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PurityLDL-R Antibody is affinity chromatography purified via peptide column.
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Ab raised inChicken
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TypePolyclonal
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ImmunoglobulinIgY
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AntigenLDL-R antibody was made against an 18 amino acid synthetic peptide near the center of human LDL-R.
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Immuno applicationELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
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Antibody adviceLDL-R antibody can be used for detection of LDL-R by Western blot at 1 - 2 ug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 ug/mL. For immunofluorescence start at 20 ug/mL.
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Suspention pH azideLDL-R Antibody is supplied in PBS containing 0.02% sodium azide.
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Keep atLDL-R antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Works withHuman, Mouse, Rat
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Omim nr4504975
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Ncbi nrNP_000518
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Vial with antibodyin solution
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Quantity per ml1 mg/mL
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NCBI GENE nr3949
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GENE symbolLDLR
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Antigene namelow density lipoprotein receptor
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SourceHomo sapiens
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Protein nrP01130
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolLDLR, LDLR-AS1, PLA2G7, RRAS, DAD1P1, HNRNPR, CLDN4, MC1R, CTNNA2, PTPRK
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Short nameanti-LDL-R Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toLDL-R (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene namelow density lipoprotein receptor
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1986-01-01
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Entrez gene record
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Classification
- Low density lipoprotein receptors
- MicroRNA protein coding host genes
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameLDLR antisense RNA 1
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Synonyms
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Locus
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Discovery year2019-08-08
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Antisense RNAs
Gene info
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Identity
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Gene
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Long gene namephospholipase A2 group VII
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Synonyms gene name
- phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-09-20
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Entrez gene record
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Pubmed identfication
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Classification
- Phospholipases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameRAS related
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Synonyms gene name
- related RAS viral (r-ras) oncogene homolog
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Synonyms
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Synonyms name
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- RAS type GTPase family
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namedefender against cell death 1 pseudogene 1
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Synonyms gene
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Synonyms gene name
- defender against cell death 1-like
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Synonyms
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Locus
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Discovery year2007-07-26
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Entrez gene record
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Pubmed identfication
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RefSeq identity
Gene info
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Identity
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Gene
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Long gene nameheterogeneous nuclear ribonucleoprotein R
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Synonyms gene
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-06-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Heterogeneous nuclear ribonucleoproteins
- RNA binding motif containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameclaudin 4
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Synonyms gene
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1998-04-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Claudins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemelanocortin 1 receptor
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Synonyms gene name
- melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
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Synonyms
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Synonyms name
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Locus
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Discovery year1993-07-27
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Melanocortin receptors
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecatenin alpha 2
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Synonyms gene name
- catenin (cadherin-associated protein), alpha 2
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Synonyms
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Synonyms name
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Locus
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Discovery year1993-07-13
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Alpha catenins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameprotein tyrosine phosphatase receptor type K
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-02-09
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Entrez gene record
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Pubmed identfication
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Classification
- Protein tyrosine phosphatases receptor type
- Fibronectin type III domain containing
- Immunoglobulin like domain containing
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data