CTBP1 Antibody

• Catalog number
  3796-100
• Price
  Please ask
• Size
  100 μl

• Antibody Target
  CTBP1
• Target Alternative Name
  CTBP, CTBP1, CTBP-1, C-Terminal Binding Protein 1
• Antibody Type
  Polyclonal
• Species Reactivities
  Human, mouse
• Immunogen Sequence
  Synthetic peptide of human CTBP1
• Accession
  Q13363
• Gene Id
  1487
• Appearance
  Colorless liquid
• Form
  Liquid
• Formulation
  100 µl affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 1% BSA and 0.02% thimerosal.
• Purification
  Affinity purified
• Application
  Western blot
• Application And Usages
  Western blotting (1:500 – 1:2000). However, the optimal concentrations should be determined individually. HeLa nuclear extract (Cat.# 1641-1) can be used as a positive control. The antibody recognizes the CTBP1 of human and mouse origins. Reactivity to other species has not been tested.
• Description
  CtBP1 is a cellular phosphoprotein that associates with various proteins and functions as a corepressor of transcription. CtBP1 and the related protein CtBP2 are characterized as C-terminal binding protein of adenovirus E1A, and they preferentially associate with the E1A via a 5-amino acid motif, PLDLS, to repress E1A induced oncogenesis and cellular transformation. CtBP1 is expressed from embryo to adult, but CtBP2 is mainly expressed during embryogenesis. During skeletal and T-cell development, CtBP1 and CtBP2 associate with the PLDLSL domain of ∂EF1, a cellular zinc finger-homeodomain protein, and thereby enhances ∂EF1 induced transcriptional silencing. In addition, CtBP complexes with CtIP, a protein that recognizes distinctly different protein motifs from CtBP. CtIP binds to the BRCT repeats within the breast cancer gene BRCA1 and enables CtBP to influence BRCA1 activity. CtIP/CtBP binding to BRCA1 inhibits the transactivation of the p21 promoter, and it is critical for regulating p21 transcription in response to DNA damage.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• FACS Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CTBP1  
• Gene symbol
  CTBP1-DT, CTBP1, CTBP1-AS
• Short name
  CTBP1 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  C-terminal binding protein 1 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  C-terminal binding protein 1, BARS, CTBP1 and IDBG-6522 and ENSG00000159692 and 1487, oxidoreductase activity, nuclei, Ctbp1 and IDBG-152845 and ENSMUSG00000037373 and 13016, CTBP1 and IDBG-643874 and ENSBTAG00000008480 and 513131

Gene info

• Identity
  HGNC:28307
• Gene
  CTBP1-DT
• Long gene name
  CTBP1 divergent transcript
• Synonyms gene
  • C4orf42
  • CTBP1-AS1
  • CTBP1-AS2
• Synonyms gene name
  • chromosome 4 open reading frame 42
  • CTBP1 antisense RNA 1 (head to head)
  • CTBP1 antisense RNA 2 (head to head)
• Synonyms
  • MGC21675
• GenBank acession
  • AK056133
• Locus
  4p16.3
• Discovery year
  2007-12-19
• Entrez gene record
  92070
• Pubmed identfication
  • 31220774
• RefSeq identity
  • NR_033339
• Classification
  • Divergent transcripts
• VEGA ID
  OTTHUMG00000160166

Gene info

• Identity
  HGNC:2494
• Gene
  CTBP1
• Long gene name
  C-terminal binding protein 1
• Synonyms
  • BARS
• Synonyms name
  • brefeldin A-ribosylated substrate
• GenBank acession
  • U37408
• Locus
  4p16.3
• Discovery year
  1997-08-22
• Entrez gene record
  1487
• Pubmed identfication
  • 9479502
• RefSeq identity
  • NM_001328
• VEGA ID
  OTTHUMG00000089259

Gene info

• Identity
  HGNC:48337
• Gene
  CTBP1-AS
• Long gene name
  CTBP1 antisense RNA
• Synonyms
  • PCAT10
• Synonyms name
  • prostate cancer associated transcript 10
• GenBank acession
  • AX747592
  • AK092548
• Locus
  4p16.3
• Discovery year
  2013-06-14
• Entrez gene record
  285463
• Pubmed identfication
  • 23644382
  • 25552498
• RefSeq identity
  • NR_104331
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000189534

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

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