anti-CNOT4 Antibody

• Catalog number
  4813
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  CNOT4 Antibody: CNOT4 is a component of the CCR4-NOT transcription complex, a complex that is implicated in the repression of RNA polymerase II transcription. In the CCR4-NOT complex, CNOT4 acts as an E3 ubiquitin-protein ligase and interacts with a subset of E2 ubiquitin-conjugating enzymes through a unique C4C4 RING domain. This E3 ligase activity was shown to be dependent on the selective and specific interaction with the ubiquitin conjugating enzyme UbcH5B. In yeast, mutations in CNOT4 that prevented its interaction with the UbcH5B homolog UBC4 caused increased sensitivity to hydroxyurea, heat shock, and hygromycin B, suggesting that CNOT4 and UbcH5B are involved in stress response in vivo. Multiple isoforms of CNOT4 are known to exist.
• Gene names
  CNOT4 Antibody: NOT4, NOT4H, CLONE243, NOT4, CCR4-NOT transcription complex subunit 4, CCR4-associated factor 4
• Antibodie s label
  unlabelled serum
• Purity
  CNOT4 Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Antigen
  CNOT4 antibody was made against a 19 amino acid synthetic peptide near the amino terminus of the human CNOT4.
• Immuno application
  ELISA, Western Blot
• Antibody advice
  CNOT4 antibody can be used for detection of CNOT4 by Western blot at 1 - 2 ug/mL.
• Suspention pH azide
  CNOT4 Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  CNOT4 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human, Mouse, Rat
• Omim nr
  56550057
• Ncbi nr
  NP_037448
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  4850
• GENE symbol
  CNOT4
• Antigene name
  CCR4-NOT transcription complex, subunit 4
• Source
  Homo sapiens
• Protein nr
  O95628
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CNOT4  
• Gene symbol
  CNOT4
• Short name
  anti-CNOT4 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toCNOT4 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:7880
• Gene
  CNOT4
• Long gene name
  CCR4-NOT transcription complex subunit 4
• Synonyms gene
  • NOT4
• Synonyms gene name
  • CCR4-NOT transcription complex, subunit 4
• Synonyms
  • CLONE243
  • NOT4H
• GenBank acession
  • AF180475
• Locus
  7q33
• Discovery year
  1996-07-19
• Entrez gene record
  4850
• Pubmed identfication
  • 10637334
  • 18533727
• RefSeq identity
  • NM_013316
• Classification
  • CCR4-NOT transcription complex
  • Ring finger proteins
  • RNA binding motif containing
• VEGA ID
  OTTHUMG00000155568

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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