anti-Neurofilament NF-H Antibody [NAP4]

  • Catalog number
    50-253
  • Price
    Please ask
  • Size
    0.1 mL
  • Gene info
    Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H. NF-H is the neurofilament high or heavy molecular weight polypeptide and runs on SDS-PAGE gels at 200-220 kDa, with some variability across species boundaries. Antibodies to NF-H are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. NF-H antibodies can also be useful to visualize neurofilament accumulations seen in many neurological diseases, such as Amyotrophic Lateral Sclerosis (Lou Gehrig's disease) and Alzheimer's disease.
  • Gene names
    NFH, KIAA0845, NFH, 200 kDa neurofilament protein, NF-H
  • Antibodie s label
    unlabelled serum
  • Purity
    Total IgG fraction
  • Ab raised in
    Mouse
  • Type
    Monoclonal
  • Monoclonal
    NAP4
  • Spicific to
    Specific for the ~200k Neurofilament H protein. It recognizes phosphorylated NF-H KSP (lysine-serine-proline) type sequences. In some species there is some cross-reactivity with the related phosphorylated KSP sequences found in the related neurofilament subunit NF-M. It recognizes neurofilaments in frozen sections in tissue culture and in formalin fixed sections.
  • Antigen
    Purified bovine NF-H.
  • Immuno application
    Western Blot, immuno-histo-chemistry
  • Keep at
    Neurofilament NF-H antibody can be stored at -20 grades C and is stable at -20 grades C for at least 1 year.
  • Works with
    Chicken, Mammal
  • Omim nr
    226726294
  • Ncbi nr
    P12036
  • KDa
    200
  • Vial with antibody
    in solution
  • NCBI GENE nr
    4744
  • GENE symbol
    NEFH
  • Antigene name
    neurofilament, heavy polypeptide
  • Source
    Homo sapiens
  • Protein nr
    P12036
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
  • Properties
    If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
  • Gene symbol
    NEFH, SOCS7, NCAPH, NFE4, NFE2, HLA-H, IGHV3-69-1, NFKB1, FUT1, PIGH
  • Short name
    anti-Neurofilament NF-H Antibody [NAP4]
  • Technique
    Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
  • Alternative name
    Antibody toNeurofilament NF-H (antibody to-) [NAP4]
  • Alternative technique
    antibodies
Gene info
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    non-SMC condensin I complex subunit H
  • Synonyms gene
  • Synonyms gene name
    • barren (Drosophila) homolog
    • barren homolog (Drosophila)
    • barren homolog 1 (Drosophila)
    • non-SMC condensin I complex, subunit H
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1998-02-11
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Condensin I subunits
    • Kleisins
  • VEGA ID
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    nuclear factor, erythroid 2
  • Synonyms gene name
    • nuclear factor (erythroid-derived 2), 45kD
    • nuclear factor (erythroid-derived 2), 45kDa
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1993-11-03
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Basic leucine zipper proteins
  • VEGA ID
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    immunoglobulin heavy variable 3-69-1 (pseudogene)
  • Synonyms gene
  • Synonyms gene name
    • immunoglobulin heavy variable 3-H (provisional)
    • immunoglobulin heavy variable 3-H pseudogene (provisional)
    • immunoglobulin heavy variable 3-H (pseudogene)
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    2000-04-04
  • Entrez gene record
  • Pubmed identfication
  • Classification
    • Immunoglobulin heavy locus at 14q32.33
  • VEGA ID
Gene info
Gene info
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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