Chk2 (NT) Polyclonal Antibody

• Catalog number
  MBS194194
• Price
  Please ask
• Size
  0.1 mg

• Products_type
  Antibody
• Products_short_name
  [Chk2 (NT)]
• Products_name_syn
  [Chk2 (NT); Chk2 (NT)]
• Other_names
  [CHK2; Serine/threonine-protein kinase Chk2; serine/threonine-protein kinase Chk2; OTTHUMP00000198969; OTTHUMP00000198970; OTTHUMP00000199044; OTTHUMP00000199045; OTTHUMP00000199064; OTTHUMP00000199115; OTTHUMP00000199116; protein kinase CHK2; checkpoint-like protein CHK2; CHK2 checkpoint homolog (S. pombe); Cds1]
• Other_gene_names
  [CHEK2; CHEK2; CDS1; CHK2; LFS2; RAD53; HuCds1; PP1425; CHK2; RAD53]
• Clonality
  Polyclonal
• Specificity
  Chk2 (NT) [This rabbit antibody recognizes an epitope of aa 2-18 at the N-terminus of human, mouse, and rat Chk2 (Checkpoint Kinase 2).] This antibody recognizes an epitope at the N-terminus of human, mouse, and rat Chk2 (Checkpoint Kinase 2). In response to DNA damage, ATM phosphorylates and activates Chk2 which in turn directly phosphorylates and activates p53. Chk2 also phosphorylates and activates BRCA1, the product of a tumor suppressor gene that is often mutated in breast and ovarian cancer.
• Form
  100 ug IgG in PBS, pH 7.4, purified by immunoaffinity chromatography.
• Storage_stability
  This antibody is stable for at least one (1) year at -20 degree C. Avoid multiple freeze-thaw cycles.
• Tested_application
  Immunoblot
• Properties
  If you buy Antibodies supplied by MyBioSource they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
• French translation
  anticorps

• Gene target
  Chk2  
• Short name
  Chk2 (NT) Polyclonal Antibody
• Technique
  Polyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Host
  Rabbit
• Alternative name
  Chk2 (NT) polyclonal (antibody to-)
• Alternative technique
  polyclonals, antibodies

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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