Anti-Centromeric histone H3-like protein-2, ALEXA Fluor 594
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Catalog numberGENTObs-0483R-A594
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PricePlease ask
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Size100 microliters
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TypeConjugated Primary Antibody
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Conjugated withALEXA FLUOR® 594
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Host organismRabbit (Oryctolagus cuniculus)
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Target Protein PeptideCentromeric histone H3-like protein-2
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SpecificityThis antibody reacts specifically with Centromeric histone H3-like protein-2
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ModificationNo modification has been applied to this antibody
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Modification siteNone
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ClonalityPolyclonal Antibody
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ClonePolyclonal Antibodies
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Concentration1ug per 1ul
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Subcellular locationsN/A
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Antigen SourceKLH conjugated synthetic peptide derived from Brassica juncea Centromeric histone H3-like protein-2
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Gene ID1058
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Swiss ProtN/A
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ApplicationsIF(IHC-P)
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Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
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Cross reactive speciesPlant
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Cross Reactive Species detailsBrassica juncea
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Background informationHistones are highly conserved proteins that serve as the structural scaffold for the organization of nuclear DNA into chromatin. The four core histones, H2A, H2B, H3, and H4, assemble into an octamer (2 molecules of each). Subsequently, 146 base pairs of DNA are wrapped around the octamer, forming a nucleosome, the basic subunit of chromatin. Histone modifications regulate DNA transcription, repair, recombination, and replication. The most commonly studied modifications are acetylation, phosphorylation, methylation, and ubiquitination. These modifications can alter local chromatin architecture, or recruit trans-acting factors that recognize specific histone modifications (the "histone code" hypothesis). Trimethylation of histone H3 on Lys9 (H3K9me3) is one of the most highly studied epigenetic marks. H3K9me3 functions in the repression of euchromatic genes, and in epigenetic control of heterochromatin assembly, most likely via acting as a recognition motif for the binding of chromatin-associated proteins, such as Swi6 or HP1Alpha/Beta. The enzymes responsible for H3K9me3 formation are SUV39H1 and SUV39H2.
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Purification methodPurified by Protein A.
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StorageWater buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
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Excitation emission590nm/617nm
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Synonymscentromere-specic H3 variant protein; Centromeric histone H3-like protein 2; Centromeric histone H3-like protein-2; cenp-A; A4P1_BRAJU.
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Also known asCentromeric histone H3-like protein-2 Antibody
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Other nameAnti-Centromeric histone H3-like protein-2
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AdvisoryAvoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
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PropertiesFor facs or microscopy Alexa 1 conjugate.
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ConjugationAlexa Fluor, ALEXA FLUOR® 594
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ConjugatedAlexa conjugate 1
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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Gene target
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Gene symbolH3-7, H3C15, H3Y2, H3Y1, H3-4, H3C14, H3C11, H3-3A-DT, H3-5, RLN3
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Short nameAnti-Centromeric histone H3-like protein-2
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Techniqueanti-, anti, antibody to, antibodies
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IsotypeImmunoglobulin G (IgG)
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LabelALEXA FLUOR 594
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Alternative nameCentromeric histone H3-like protein-2 Antibody, ALEXA FLUOR® 594 Conjugated
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameH3.7 histone (putative)
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Synonyms gene
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Synonyms gene name
- histone 2, H3, pseudogene 2
- histone cluster 2, H3, pseudogene 2
- histone cluster 2 H3 pseudogene 2
- H3.2 histone (putative)
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Synonyms
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GenBank acession
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Locus
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Discovery year2006-06-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- H3 histones
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameH3 clustered histone 15
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Synonyms gene
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Synonyms gene name
- histone 2, H3a
- histone cluster 2, H3a
- histone cluster 2 H3 family member a
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Synonyms
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GenBank acession
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Locus
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Discovery year2003-02-19
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Entrez gene record
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Pubmed identfication
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Classification
- H3 histones
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameH3.Y histone 2
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Synonyms
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Locus
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Discovery year2019-08-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- H3 histones
Gene info
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Identity
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Gene
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Long gene nameH3.Y histone 1
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Synonyms
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Locus
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Discovery year2019-08-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- H3 histones
Gene info
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Identity
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Gene
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Long gene nameH3.4 histone
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Synonyms gene
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Synonyms gene name
- H3 histone family, member T
- histone 3, H3
- histone cluster 3, H3
- histone cluster 3 H3
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-09-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- H3 histones
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameH3 clustered histone 14
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Synonyms gene
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Synonyms gene name
- H3 histone family, member M
- histone 2, H3c
- histone cluster 2, H3c
- histone cluster 2 H3 family member c
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Synonyms
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GenBank acession
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Locus
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Discovery year2003-02-19
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- H3 histones
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameH3 clustered histone 11
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Synonyms gene
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Synonyms gene name
- H3 histone family, member F
- histone 1, H3i
- histone cluster 1, H3i
- histone cluster 1 H3 family member i
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-08-27
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- H3 histones
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameH3-3A divergent transcript
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Locus
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Discovery year2020-08-21
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Classification
- Divergent transcripts
Gene info
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Identity
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Gene
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Long gene nameH3.5 histone
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Synonyms gene
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Synonyms gene name
- H3 histone, family 3C
- H3 histone family member 3C
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Synonyms
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GenBank acession
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Locus
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Discovery year2009-08-13
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- H3 histones
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namerelaxin 3
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Synonyms gene name
- relaxin 3 (H3)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2001-11-16
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Entrez gene record
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Classification
- Neuropeptides
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data