anti-EBP Antibody
-
Catalog number30-224
-
PricePlease ask
-
Size50 ug
-
-
Gene infoEBP is an integral membrane protein of the endoplasmic reticulum. It is a high affinity binding protein for the antiischemic phenylalkylamine Ca2+ antagonist [3H]emopamil and the photoaffinity label [3H]azidopamil. It is similar to sigma receptors and may be a member of a superfamily of high affinity drug-binding proteins in the endoplasmic reticulum of different tissues. These aromatic amino acid residues have been suggested to be involved in the drug transport by the P-glycoprotein. Mutations in EBP gene cause Chondrodysplasia punctata 2 (CDPX2; also known as Conradi-Hunermann syndrome).Emopamil-binding protein (EBP) is an integral membrane protein of the endoplasmic reticulum. It is a high affinity binding protein for the antiischemic phenylalkylamine Ca2+ antagonist [3H]emopamil and the photoaffinity label [3H]azidopamil. It is similar to sigma receptors and may be a member of a superfamily of high affinity drug-binding proteins in the endoplasmic reticulum of different tissues. EBP shares structural features with bacterial and eukaryontic drug transporting proteins. It has four putative transmembrane segments and contains two conserved glutamate residues which may be involved in the transport of cationic amphiphilics. Another prominent feature of EBP is its high content of aromatic amino acid residues (>23%) in its transmembrane segments. These aromatic amino acid residues have been suggested to be involved in the drug transport by the P-glycoprotein. Mutations in this gene cause Chondrodysplasia punctata 2 (CDPX2; also known as Conradi-Hunermann syndrome).
-
Gene namesEBP, CDPX2, CHO2, CPX, CPXD
-
Antibodie s labelunlabelled serum
-
PurityAntibody is purified by peptide affinity chromatography method.
-
Ab raised inRabbit
-
TypePolyclonal
-
AntigenAntibody produced in rabbits immunized with a synthetic peptide corresponding a region of human EBP.
-
Immuno applicationELISA, Western Blot
-
Antibody adviceEBP antibody can be used for detection of EBP by ELISA at 1:12500. EBP antibody can be used for detection of EBP by western blot at 0.5 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
-
Suspention pH azideAntibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
-
Keep atFor short periods of storage (days) store at 4 grades C. For longer periods of storage, store EBP antibody at -20 grades C. As with any antibody avoid repeat freeze-thaw cycles.
-
Works withHuman
-
Omim nr5729810
-
Ncbi nrNP_006570
-
KDa26 kDa
-
Vial with antibodyLyophilized
-
Quantity per ml1 mg/ml
-
NCBI GENE nr10682
-
GENE symbolEBP
-
Antigene nameemopamil binding protein (sterol isomerase)
-
SourceHomo sapiens
-
Protein nrQ15125
-
DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
-
PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translationanticorps
-
Gene target
-
Gene symbolGLB1, EBP, CEBPG, CEBPA, FCN2, SH3D19, CEBPB, CEBPD
-
Short nameanti-EBP Antibody
-
TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
-
Alternative nameAntibody toEBP (antibody to-)
-
Alternative techniqueantibodies
-
Gene info
-
Identity
-
Gene
-
Long gene namegalactosidase beta 1
-
Synonyms gene
-
Synonyms gene name
- elastin receptor 1, 67kDa
- elastin receptor 1 (67kD)
- galactosidase, beta 1
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year2001-06-22
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Galactosidases beta
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameEBP cholestenol delta-isomerase
-
Synonyms gene
-
Synonyms gene name
- emopamil-binding protein (sterol isomerase)
- emopamil binding protein (sterol isomerase)
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year2000-02-21
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameCCAAT enhancer binding protein gamma
-
Synonyms gene name
- CCAAT/enhancer binding protein (C/EBP), gamma
- CCAAT/enhancer binding protein gamma
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1992-07-08
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Basic leucine zipper proteins
- CCAAT/enhancer binding proteins
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameCCAAT enhancer binding protein alpha
-
Synonyms gene
-
Synonyms gene name
- CCAAT/enhancer binding protein (C/EBP), alpha
- CCAAT/enhancer binding protein alpha
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1991-11-27
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Basic leucine zipper proteins
- CCAAT/enhancer binding proteins
-
VEGA ID
-
Locus Specific Databases
Gene info
-
Identity
-
Gene
-
Long gene nameficolin 2
-
Synonyms gene name
- ficolin (collagen/fibrinogen domain-containing lectin) 2 (hucolin)
- ficolin (collagen/fibrinogen domain containing lectin) 2
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1996-07-11
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Complement system activation components
- Fibrinogen C domain containing
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameSH3 domain containing 19
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year2008-02-18
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameCCAAT enhancer binding protein beta
-
Synonyms gene
-
Synonyms gene name
- CCAAT/enhancer binding protein (C/EBP), beta
- CCAAT/enhancer binding protein beta
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1991-02-27
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Basic leucine zipper proteins
- CCAAT/enhancer binding proteins
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameCCAAT enhancer binding protein delta
-
Synonyms gene name
- CCAAT/enhancer binding protein (C/EBP), delta
- CCAAT/enhancer binding protein delta
-
Synonyms
-
Locus
-
Discovery year1992-06-24
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Basic leucine zipper proteins
- CCAAT/enhancer binding proteins
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
