anti-Integrin alpha 4 Antibody

  • Catalog number
    4827
  • Price
    Please ask
  • Size
    0.02 mg, 0.1 mg
  • Gene info
    Integrin alpha 4 Antibody: The integrin alpha 4 (also known as CD49d and ITGA4) belongs to the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha and beta chains. Alpha4 chain associates with either beta1 or beta7 chain. It has been demonstrated that the putative ligand-binding sites of both integrin alpha4beta1 and alpha4beta7 is located on the alpha4 chain. These ligands included Madcam, VCAM, and fibronectin. Madcam is known as the principal ligand for integrin alpha4beta7. Recently it was also demonstrated that HIV-1 envelope can mimic Madcam by binding to and signaling though integrin alpha4beta1, the gut mucosal homing receptor for peripheral T cells. At least two isoforms are known to exist.
  • Gene names
    Integrin alpha 4 Antibody: IA4, CD49D, Integrin alpha-4, CD49 antigen-like family member D
  • Antibodie s label
    unlabelled serum
  • Purity
    Integrin alpha 4 Antibody is affinity chromatography purified via peptide column.
  • Ab raised in
    Rabbit
  • Type
    Polyclonal
  • Immunoglobulin
    IgG
  • Antigen
    Integrin alpha 4 antibody was made against a 16 amino acid synthetic peptide from near the center of human Integrin alpha 4.
  • Immuno application
    ELISA, Western Blot, immuno fluorescence
  • Antibody advice
    Integrin alpha 4 antibody can be used for the detection of Integrin alpha 4 by Western blot at 1 ug/mL. Despite its predicted molecular weight, Integrin alpha4 will often run at higher molecular weight in SDS-PAGE. Antibody can also be used for immunoflourescence starting at 2 ug/mL.
  • Suspention pH azide
    Integrin alpha 4 Antibody is supplied in PBS containing 0.02% sodium azide.
  • Keep at
    Integrin alpha 4 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Works with
    Human, Mouse, Rat
  • Omim nr
    67191027
  • Ncbi nr
    NP_000876
  • Vial with antibody
    in solution
  • Quantity per ml
    1 mg/mL
  • NCBI GENE nr
    3676
  • GENE symbol
    ITGA4
  • Antigene name
    integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
  • Source
    Homo sapiens
  • Protein nr
    P13612
  • Description
    The anti-Integrin alpha 4 Antibody is a α- or alpha protein sometimes glycoprotein present in blood. This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
  • Properties
    If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    Integrin   alpha  
  • Gene symbol
    ITGA9, ITGA4, ITGAX
  • Short name
    anti-Integrin alpha 4 Antibody
  • Technique
    Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
  • Alternative name
    Antibody toIntegrin a 4 (antibody to-)
  • Alternative technique
    antibodies
Gene info
Gene info
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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