anti-CBX3 Antibody

• Catalog number
  28-174
• Price
  Please ask
• Size
  50 ug

• Gene info
  At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. CBX3 binds DNA and is a component of heterochromatin. CBX3 also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of CBX3 may explain the association of heterochromatin with the inner nuclear membrane.At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.
• Gene names
  CBX3, HECH, HP1-GAMMA, HP1Hs-gamma
• Antibodie s label
  unlabelled serum
• Purity
  Antibody is purified by peptide affinity chromatography method.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Antigen
  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CBX3.
• Immuno application
  ELISA, Western Blot
• Antibody advice
  CBX3 antibody can be used for detection of CBX3 by ELISA at 1:12500. CBX3 antibody can be used for detection of CBX3 by western blot at 0.25 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
• Suspention pH azide
  Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
• Keep at
  For short periods of storage (days) store at 4 grades C. For longer periods of storage, store CBX3 antibody at -20 grades C. As with any antibody avoid repeat freeze-thaw cycles.
• Works with
  Human, Mouse, Rat, Dog
• Omim nr
  15082258
• Ncbi nr
  NP_009207
• KDa
  21 kDa
• Vial with antibody
  Lyophilized
• Quantity per ml
  1 mg/ml
• NCBI GENE nr
  11335
• GENE symbol
  CBX3
• Antigene name
  chromobox homolog 3
• Source
  Homo sapiens
• Protein nr
  Q13185
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CBX3  
• Gene symbol
  CBX3
• Short name
  anti-CBX3 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toCBX3 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:1553
• Gene
  CBX3
• Long gene name
  chromobox 3
• Synonyms gene name
  • chromobox homolog 3 (Drosophila HP1 gamma)
  • chromobox homolog 3
• Synonyms
  • HP1Hs-gamma
• Synonyms name
  • HP1 gamma homolog (Drosophila)
• GenBank acession
  • U26312
• Locus
  7p15.2
• Discovery year
  1999-10-12
• Entrez gene record
  11335
• Pubmed identfication
  • 8663349
• RefSeq identity
  • NM_007276
• Classification
  • Chromobox family
• VEGA ID
  OTTHUMG00000022911

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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