CD144 (VE-Cadherin) Antibody

  • Catalog number
    A1148-100
  • Price
    Please ask
  • Size
    100 µl
  • Antibody Target
    CDH5
  • Target Alternative Name
    Cadherin-5; 7B4 antigen; Vascular endothelial cadherin; VE-cadherin; CD144
  • Antibody Type
    Polyclonal
  • Species Reactivities
    Human, Mouse
  • Immunogen Sequence
    KLH-conjugated synthetic peptide encompassing a sequence within the center region of human CD144
  • Accession
    P33151
  • Gene Id
    1003
  • Appearance
    Colorless liquid
  • Form
    Liquid
  • Formulation
    In 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol and 0.01% sodium azide
  • Purification
    Affinity purified
  • Application
    WB
  • Positive Control
    WB: HeLa, mouse lung, mouse heart lysates
  • Application And Usages
    WB; 1:500 – 1:2000
  • Description
    Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha-catenin forming a link to the cytoskeleton. Acts in concert with KRIT1 to establish and maintain correct endothelial cell polarity and vascular lumen. These effects are mediated by recruitment and activation of the Par polarity complex and RAP1B. Required for activation of PRKCZ and for the localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction.
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    12 months
  • Usage
    For Research Use Only! Not to be used in humans
  • Handling
    The antibody solution should be gently mixed before use
  • Western Blot Verified
    Verified
  • Immunocytochemistry Verified
    Not Verified
  • Immunofluorescence Verified
    Not Verified
  • Immunoprecipitation Verified
    Not Verified
  • FACS Verified
    Not Verified
  • ELISA Verified
    Not Verified
  • ChIP Verified
    Not Verified
  • Dot Blot Verified
    Not Verified
  • Flow Cytometry Verified
    Not Verified
  • Properties
    If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
  • Gene symbol
    JAM2, CDH5
  • Short name
    CD144 (VE-Cadherin) Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Isotype
    Rabbit IgG
  • Alternative name
    CD144 (VE-Cadherin) (antibody to-)
  • Alternative technique
    antibodies
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    cadherin 5
  • Synonyms gene name
    • cadherin 5, type 2, VE-cadherin (vascular epithelium)
    • cadherin 5, type 2 (vascular endothelium)
  • Synonyms
  • Synonyms name
  • GenBank acession
  • Locus
  • Discovery year
    1992-11-20
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Type II classical cadherins
    • CD molecules
  • VEGA ID
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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