IP3 Receptor Antibody, ALEXA FLUOR 594

• Catalog number
  bs-8869R-A594
• Price
  Please ask
• Size
  100ul

• Long name
  IP3 Receptor Polyclonal Antibody, ALEXA FLUOR 594 Conjugated
• Also known as
  Anti-IP3 Receptor PAb ALEXA FLUOR 594
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 594
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  IP3 Receptor
• Specificity
  This is a highly specific antibody against IP3 Receptor.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  110-160/2758
• Subcellular location
  Cytoplasm
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human IP3 Receptor
• Gene ID Number
  3708
• Swiss Prot
  Q14643
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity).
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  590nm/617nm
• Synonyms
  ACV; CLA4; IP3R; IP3R1; SCA15; SCA16; SCA29; INSP3R1; PPP1R94; Inositol 1,4,5-trisphosphate receptor type 1; IP3 receptor isoform 1; IP3R 1; Type 1 inositol 1,4,5-trisphosphate receptor; Type 1 InsP3 receptor; ITPR1
• Properties
  For facs or microscopy Alexa 1 conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR® 594
• Conjugated
  Alexa conjugate 1
• Description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• French translation
  anticorps

• Gene target
  IP3   Receptor  
• Gene symbol
  ITPKB, ITPKA, ITPKC, CFAP61
• Short name
  Anti-IP3 Receptor
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 594
• Alternative name
  IP3 Receptor Polyclonal Antibody, ALEXA FLUOR 594
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:6179
• Gene
  ITPKB
• Long gene name
  inositol-trisphosphate 3-kinase B
• Synonyms gene name
  • inositol 1,4,5-trisphosphate 3-kinase B
• Synonyms
  • IP3KB
  • IP3-3KB
• GenBank acession
  • AJ242780
• Locus
  1q42.12
• Discovery year
  1992-04-15
• Entrez gene record
  3707
• Pubmed identfication
  • 1654894
  • 1330886
• RefSeq identity
  • NM_002221
• VEGA ID
  OTTHUMG00000037582

Gene info

• Identity
  HGNC:6178
• Gene
  ITPKA
• Long gene name
  inositol-trisphosphate 3-kinase A
• Synonyms gene name
  • inositol 1,4,5-trisphosphate 3-kinase A
• Synonyms
  • IP3KA
  • IP3-3KA
• GenBank acession
  • X54938
• Locus
  15q15.1
• Discovery year
  1992-04-15
• Entrez gene record
  3706
• Pubmed identfication
  • 1330886
  • 2175886
• RefSeq identity
  • NM_002220
• VEGA ID
  OTTHUMG00000130343

Gene info

• Identity
  HGNC:14897
• Gene
  ITPKC
• Long gene name
  inositol-trisphosphate 3-kinase C
• Synonyms gene name
  • inositol 1,4,5-trisphosphate 3-kinase C
• Synonyms
  • IP3KC
  • IP3-3KC
• GenBank acession
  • Y11999
• Locus
  19q13.2
• Discovery year
  2001-06-28
• Entrez gene record
  80271
• Pubmed identfication
  • 11085927
• RefSeq identity
  • NM_025194
• VEGA ID
  OTTHUMG00000182688

Gene info

• Identity
  HGNC:15872
• Gene
  CFAP61
• Long gene name
  cilia and flagella associated protein 61
• Synonyms gene
  • C20orf26
• Synonyms gene name
  • chromosome 20 open reading frame 26
• Synonyms
  • DKFZP434K156
  • dJ1002M8.3
  • CaM-IP3
• Synonyms name
  • hypothetical protein LOC26074
• GenBank acession
  • AL117439
• Locus
  20p11.23
• Discovery year
  2001-06-21
• Entrez gene record
  26074
• Pubmed identfication
  • 11780052
  • 17967944
• RefSeq identity
  • NM_015585
• Classification
  • Cilia and flagella associated
• VEGA ID
  OTTHUMG00000032006

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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