anti BRD2 Antibody

anti BRD2 Antibody is available 2 times from Biovision labs

6281-100 | anti-BRD2 Antibodysize: BRD2 Antibody | 406.52 USD

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6281-30T | anti-BRD2 Antibodysize: BRD2 Antibody | 171.23 USD

  • Catalog number
    6281-30T
  • Supplier
  • Price
    171.23 USD
  • Size
    BRD2 Antibody
  • Formulation of this antibody:
    30 µg (0.5 mg/ml) of antibody in PBS, 0.01 % BSA, 0.01 % thimerosal, and 50 % glycerol, pH 7.2
1. Gene info
2. Gene info
MeSH Data
  • Name
  • Concept
    Scope note:Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
Additional information
Product images
  • Target of this antibody:
    BRD2
  • Alternative names of antibody target:
    RING3, RNF3; Bromodomain containing 4
  • Background information:
    The acetylation of histone lysine residues plays a crucial role in the epigenetic regulation of gene transcription. A bromodomain is a protein domain that recognizes acetylated lysine residues such as those on the N-terminal tails of histones. This recognition is often a prerequisite for protein-histone association and chromatin remodeling. These domains function in the linking of protein complexes to acetylated nucleosomes, thereby controlling chromatin structure and gene expression. Thus, bromodomains serve as “readers” of histone acetylation marks regulating the transcription of target promoters. The BET family of proteins, defined by tandem Bromodomains and an Extra Terminal domain, include BRD2, BRD3, BRD4, and BRDT. The BET proteins play a key role in many cellular processes, including inflammatory gene expression, mitosis, and viral/host interactions. The isolated individual or tandem bromodomains of BRD2 and BRD4 have been shown to bind acetylated histone tails, serving to couple histone acetylation marks to the transcriptional regulation of target promoters. Small molecule inhibitors of these interactions hold promise as useful therapeutics for human disease.
  • Antibody host:
    Rabbit
  • Clonality of antibody:
    Polyclonal
  • Isotype:
    Rabbit IgG
  • This antibody reacts with:
    Human, mouse, rat
  • Immunogene sequence:
    Synthetic peptide at N-terminal
  • Concentration of antibody:
    0.5 mg/ml
  • Form of antibody:
    Liquid
  • Purification method:
    Affinity purified antibody
  • This antibody has been succesfully tested for use in following methods:
    Western blot
  • Recommended usage:
    Western blot: 1:200
  • Storage information:
    Shelf time: 12 months in temp.: -20 deg.C
  • Shipping conditions:
    gel pack
  • How to handle this antibody:
    The antibody solution should be gently mixed before use.
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
  • Properties
    If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
  • Short name
    anti-BRD2 Antibody
  • Technique
    Antibody, anti
  • Alternative name
    antibody to-BRD2 (Antibody to)
  • Alternative technique
    antibodies
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anti BRD2 Antibody - Gentaur.com
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