Bok Antibody
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Catalog number3043-100
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PricePlease ask
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Size100 µg
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Antibody TargetBok
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Target Alternative NameBcl-2-related ovarian killer
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Antibody TypePolyclonal
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Species ReactivitiesMouse, rat
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Immunogen SequenceSynthetic peptide surrounding amino acid 44 of rat BOK
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AccessionEAW71269
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Gene Id666
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AppearanceColorless liquid
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FormLiquid
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Concentration0.2 mg/ml
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Formulation100 µg (0.2 mg/ml) peptide affinity purified rabbit anti-Bok polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal.
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PurificationAffinity purified
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ApplicationWestern blot
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Application And UsagesWestern blot analysis (0.5-4 µg/ml).
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DescriptionBok (Bcl-2-related ovarian killer) is a pro-apoptotic Bcl-2 family protein identified in the ovary based on its dimerization with the anti-apoptotic protein Mcl-1. In addition to the Bcl-2 homology (BH) domains 1 and 2 and the transmembrane sequence, Bok also has a BH3 domain believed to be important for dimerization with selective anti-apoptotic Bcl-2 proteins and cell killing. Bok interacts strongly with some (Mcl-1, BHRF1, and Bfl-1) but not other (Bcl-2, Bcl-xL, and Bcl-w) anti-apoptotic members. In addition, cell killing induced by Bok was suppressed following coexpression with Mcl-1 and BHRF1, but not with Bcl-2, further indicating that Bok heterodimerized only with selective anti-apoptotic Bcl-2 proteins. Bok was highly expressed in the ovary, testis and uterus.
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Storage Condition-20 °C
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Shipping Conditiongel pack
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Shelf Life12 months
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UsageFor Research Use Only! Not to be used in humans.
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HandlingThe antibody solution should be gently mixed before use.
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Western Blot VerifiedVerified
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Immunocytochemistry VerifiedNot Verified
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Immunofluorescence VerifiedNot Verified
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Immunoprecipitation VerifiedNot Verified
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FACS VerifiedNot Verified
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ELISA VerifiedNot Verified
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ChIP VerifiedNot Verified
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Dot Blot VerifiedNot Verified
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Flow Cytometry VerifiedNot Verified
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PropertiesIf you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolBOK-AS1, BOK
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Short nameBok Antibody
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit IgG
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Alternative nameBCL2-related ovarian killer (antibody to-)
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Alternative techniqueantibodies
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Alternative to gene targetBCL2-related ovarian killer, BCL2L9 and BOKL, BOK and IDBG-85207 and ENSG00000176720 and 666, BH domain binding, nuclei, Bok and IDBG-183725 and ENSMUSG00000026278 and 51800, BOK and IDBG-642666 and ENSBTAG00000008711 and 504851
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Gene info
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Identity
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Gene
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Long gene nameBOK antisense RNA 1
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Synonyms gene
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Synonyms gene name
- BOK antisense RNA (non-protein coding)
- BOK antisense RNA 1 (non-protein coding)
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Synonyms
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Synonyms name
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Locus
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Discovery year2009-07-29
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Antisense RNAs
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameBCL2 family apoptosis regulator BOK
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Synonyms gene name
- BCL2 related ovarian killer
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-01-20
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- BCL2 family
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
