anti-GDF6 Antibody

• Catalog number
  4691
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  GDF6 Antibody: Growth differentiation factors (GDFs) are members of the transforming growth factor (TGF) superfamily that is involved in embryonic development and adult tissue homeostasis. Both GDF6 and GDF7 are closely related to GDF5 which has been shown to induce activation of plasminogen activator, thereby inducing angiogenesis. It is predominantly expressed in long bones during fetal embryonic development and is involved in bone formation. In Xenopus, GDF6 is expressed at the edge of the neural plate and within the anterior neural plate including the eye fields. GDF6 is required for normal formation of some bones and joints in the limbs, skull, and axial skeleton. It may regulate patterning of the ectoderm by interacting with bone morphogenetic proteins (BMPs), and control eye development. Mutations in this gene result in colobomata, which are congenital abnormalities in ocular development, and in Klippel-Feil syndrome (KFS), a congenital disorder of spinal segmentation.
• Gene names
  GDF6 Antibody: KFM, KFS, KFS1, KFSL, SGM1, BMP13, CDMP2, LCA17, MCOP4, SCDO4, MCOPCB6, GDF16GDF-6
• Antibodie s label
  unlabelled serum
• Purity
  GDF6 Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Antigen
  GDF6 antibody was made against a 17 amino acid synthetic peptide near the carboxy terminus of the human GDF6.
• Immuno application
  ELISA, Western Blot
• Antibody advice
  GDF6 antibody can be used for detection of GDF6 by Western blot at 0.5 to 1 ug/mL.
• Suspention pH azide
  GDF6 Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  GDF6 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human, Mouse, Rat
• Omim nr
  48475062
• Ncbi nr
  NP_001001557
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  392255
• GENE symbol
  GDF6
• Antigene name
  growth differentiation factor 6
• Source
  Homo sapiens
• Protein nr
  Q6KF10
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  GDF6  
• Gene symbol
  GDF6
• Short name
  anti-GDF6 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toGDF6 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  growth differentiation factor 6, GDF6 and IDBG-29375 and ENSG00000156466 and 392255, protein homodimerization activity, Extracellular, Gdf6 and IDBG-129105 and ENSMUSG00000051279 and 242316, BT.29849 and IDBG-645217 and ENSBTAG00000007687 and 407175

Gene info

• Identity
  HGNC:4221
• Gene
  GDF6
• Long gene name
  growth differentiation factor 6
• Synonyms gene
  • SGM1
• Synonyms gene name
  • segmentation syndrome 1
• Synonyms
  • BMP13
  • KFS
  • KFS1
• Locus
  8q22.1
• Discovery year
  1999-04-23
• Entrez gene record
  392255
• Pubmed identfication
  • 10022976
  • 18425797
• RefSeq identity
  • NM_001001557
• Classification
  • Transforming growth factor beta superfamily
• VEGA ID
  OTTHUMG00000164710

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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