anti-NOD2 Antibody

• Catalog number
  2511
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  NOD2 Antibody: Apaf-1 and NOD1 are members of a new family, which are involved in the regulation of apoptosis and immune response. Each of them contains a caspase recruitment domain (CARD) and a nucleotide-binding oligomerization domain (NOD). A third member in this family was recently identified and designated NOD2. NOD2 interacts with RICK via a homophilic CARD-CARD interaction. NOD2 activates NF-kB, which is regulated by its carboxy-terminal leucine-rich repeat domain that acts as an intracellular receptor for components of bacteria. The variants of NOD2, either a frameshift or a missense, were associated with Crohn's disease that is a main type of chronic inflammatory bowel disease.
• Gene names
  NOD2 Antibody: CD, ACUG, BLAU, IBD1, NLRC2, NOD2B, CARD15, CLR16.3, PSORAS1, Nucleotide-binding oligomerization domain-containing protein 2, Caspase recruitment domain-containing protein 15
• Antibodie s label
  unlabelled serum
• Purity
  NOD2 Antibody is immunoaffinity chromatography purified IgG.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Spicific to
  NOD2 has no cross-reaction with NOD1.
• Antigen
  Rabbit NOD2 polyclonal antibody was made against a synthetic peptide corresponding to 16 amino acids at the amino terminus of human NOD2.
• Immuno application
  ELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
• Antibody advice
  NOD2 antibody can be used for detection of Noxa by Western blot at 1 to 4 ug/mL. Antibody can also be used for immunohistochemistry starting at 5 ug/mL. For immunofluorescence start at 10 ug/mL.
• Suspention pH azide
  NOD2 Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  NOD2 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human
• Omim nr
  20137973
• Ncbi nr
  Q9HC29
• Vial with antibody
  in solution
• NCBI GENE nr
  64127
• GENE symbol
  NOD2
• Antigene name
  nucleotide-binding oligomerization domain containing 2
• Source
  Homo sapiens
• Protein nr
  Q9HC29
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  NOD2  
• Gene symbol
  NOD2
• Short name
  anti-NOD2 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toNOD2 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  nucleotide-binding oli this GO merization domain containing 2, NOD2 and IDBG-30654 and ENSG00000167207 and 64127, CARD domain binding, Cell surfaces, Nod2 and IDBG-179050 and ENSMUSG00000055994 and 257632, NOD2 and IDBG-631640 and ENSBTAG00000020936 and 444867

Gene info

• Identity
  HGNC:5331
• Gene
  NOD2
• Long gene name
  nucleotide binding oligomerization domain containing 2
• Synonyms gene
  • IBD1
  • CARD15
• Synonyms gene name
  • caspase recruitment domain family, member 15
• Synonyms
  • BLAU
  • CD
  • PSORAS1
  • CLR16.3
  • NLRC2
• Synonyms name
  • nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 2
  • NOD-like receptor C2
  • NLR family, CARD domain containing 2
• GenBank acession
  • AF178930
• Locus
  16q12.1
• Discovery year
  1998-07-10
• Entrez gene record
  64127
• Pubmed identfication
  • 7809109
  • 8587604
• RefSeq identity
  • NM_022162
• Classification
  • NLR family
  • Caspase recruitment domain containing
• VEGA ID
  OTTHUMG00000133171
• Locus Specific Databases
  • LRG_177

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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