Anti-MCL1 (Polyclonal), ALEXA Fluor 594

  • Catalog number
    GENTObs-1352R-A594
  • Price
    Please ask
  • Size
    100 microliters
  • Type
    Conjugated Primary Antibody
  • Conjugated with
    ALEXA FLUOR® 594
  • Host organism
    Rabbit (Oryctolagus cuniculus)
  • Target Protein Peptide
    MCL1
  • Specificity
    This antibody reacts specifically with MCL1
  • Modification
    No modification has been applied to this antibody
  • Modification site
    None
  • Clonality
    Polyclonal Antibody
  • Clone
    Polyclonal Antibodies
  • Concentration
    1ug per 1ul
  • Subcellular locations
    Helical
  • Antigen Source
    KLH conjugated synthetic peptide derived from human MCL1
  • Gene ID
    4170
  • Swiss Prot
    Q07820
  • Applications
    IF(IHC-P)
  • Applications with corresponding dilutions
    IF(IHC-P)(1:50-200)
  • Cross reactive species
    Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
  • Cross Reactive Species details
    No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
  • Background information
    Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.
  • Purification method
    Purified by Protein A.
  • Storage
    Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
  • Excitation emission
    590nm/617nm
  • Synonyms
    TM; EAT; MCL1L; MCL1S; Mcl-1; BCL2L3; MCL1-ES; bcl2-L-3; mcl1/EAT; Induced myeloid leukemia cell differentiation protein Mcl-1; Bcl-2-like protein 3; Bcl-2-related protein EAT/mcl1; MCL1
  • Also known as
    MCL1 Polyclonal Antibody
  • Other name
    Anti-MCL1 Polyclonal
  • Advisory
    Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
  • Properties
    For facs or microscopy Alexa 1 conjugate.
  • Conjugation
    Alexa Fluor, ALEXA FLUOR® 594
  • Conjugated
    Alexa conjugate 1
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
  • Group
    Polyclonals and antibodies
  • About
    Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
  • Gene target
    MCL1  
  • Gene symbol
    MCL1
  • Short name
    Anti-MCL1
  • Technique
    Polyclonal, anti-, anti, antibody to, antibodies, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
  • Isotype
    Immunoglobulin G (IgG)
  • Label
    ALEXA FLUOR 594
  • Alternative name
    MCL1 Polyclonal Antibody, ALEXA FLUOR® 594 Conjugated
  • Alternative technique
    polyclonals, antibodies
  • Alternative to gene target
    myeloid cell leukemia sequence 1 (BCL2-related), bcl2-L-3 and BCL2L3 and EAT and Mcl-1 and MCL1-ES and mcl1/EAT and MCL1L and MCL1S and TM, MCL1 and IDBG-102145 and ENSG00000143384 and 4170, BH3 domain binding, nuclei, Mcl1 and IDBG-173221 and ENSMUSG00000038612 and 17210
Gene info
  • Identity
  • Gene
  • Long gene name
    MCL1 apoptosis regulator, BCL2 family member
  • Synonyms gene name
    • myeloid cell leukemia sequence 1 (BCL2-related)
    • myeloid cell leukemia 1
    • MCL1, BCL2 family apoptosis regulator
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1993-11-09
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • BCL2 family
  • VEGA ID
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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