anti-BAG2 Antibody

• Catalog number
  29-709
• Price
  Please ask
• Size
  100 ug

• Gene info
  BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.
• Gene names
  BAG2, RP3-496N17.2, BAG-2, KIAA0576, MGC149462, dJ417I1.2
• Antibodie s label
  unlabelled serum
• Purity
  Antibody is purified by protein A chromatography method.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Antigen
  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human BAG2.
• Immuno application
  ELISA, Western Blot, immuno-histo-chemistry
• Antibody advice
  BAG2 antibody can be used for detection of BAG2 by ELISA at 1:1562500. BAG2 antibody can be used for detection of BAG2 by western blot at 1.25 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
• Suspention pH azide
  Antibody is lyophilized in PBS buffer with 2% sucrose. Add 100 μL of distilled water. Final antibody concentration is 1 mg/mL.
• Keep at
  For short periods of storage (days) store at 4 grades C. For longer periods of storage, store BAG2 antibody at -20 grades C. As with any antibody avoid repeat freeze-thaw cycles.
• Works with
  Human, Mouse, Rat, Dog, Zebrafish
• Omim nr
  4757834
• Ncbi nr
  NP_004273
• KDa
  23 kDa
• Vial with antibody
  Lyophilized
• Quantity per ml
  1 mg/ml
• NCBI GENE nr
  9532
• GENE symbol
  BAG2
• Antigene name
  BCL2-associated athanogene 2
• Source
  Homo sapiens
• Protein nr
  O95816
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  BAG2  
• Gene symbol
  BAG2
• Short name
  anti-BAG2 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toBAG2 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  BCL2-associated athanogene 2, BAG-2 and dJ417I1.2, BAG2 and IDBG-91571 and ENSG00000112208 and 9532, chaperone binding, multiple, Bag2 and IDBG-140714 and ENSMUSG00000042215 and 213539, BAG2 and IDBG-628617 and ENSBTAG00000005355 and 506107

Gene info

• Identity
  HGNC:938
• Gene
  BAG2
• Long gene name
  BAG cochaperone 2
• Synonyms gene name
  • BCL2 associated athanogene 2
• GenBank acession
  • AF095192
• Locus
  6p12.1
• Discovery year
  1999-04-23
• Entrez gene record
  9532
• Pubmed identfication
  • 9873016
• Classification
  • BAG cochaperones
• VEGA ID
  OTTHUMG00000014919

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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