anti-AXIN1 Antibody

• Catalog number
  6005
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  AXIN1 Antibody: AXIN1 is a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain and is thought to function as a negative regulator of the WNT signaling pathway that regulates embryonic axis formation. AXIN1 interacts with adenomatosis polyposis coli (APC), beta-catenin, glycogen synthase kinase 3 beta, forming a tetrameric complex resulting in the regulation of the stabilization of beta-catenin. Mutations in the AXIN1 gene have been associated various carcinomas, indicating that it also functions as a tumor suppressor.
• Gene names
  AXIN1 Antibody: AXIN, PPP1R49, AXIN, Axin-1, Axis inhibition protein 1, hAxin
• Antibodie s label
  unlabelled serum
• Purity
  AXIN1 Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Antigen
  AXIN1 antibody was made against a 14 amino acid synthetic peptide near the carboxy terminus of human AXIN1.
• Immuno application
  ELISA, Western Blot, immuno fluorescence
• Antibody advice
  AXIN1 antibody can be used for detection of AXIN1 by Western blot at 1 - 2 ug/mL. Antibody can also be used for immunoflourescence starting at 20 ug/mL. For immunofluorescence start at 20 ug/mL.
• Suspention pH azide
  AXIN1 Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  AXIN1 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human, Mouse, Rat
• Omim nr
  2252820
• Ncbi nr
  AAC51624
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  8312
• GENE symbol
  AXIN1
• Antigene name
  axin 1
• Source
  Homo sapiens
• Protein nr
  O15169
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  AXIN1  
• Gene symbol
  AXIN1
• Short name
  anti-AXIN1 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toAXIN1 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  axin 1, AXIN and PPP1R49, AXIN1 and IDBG-7404 and ENSG00000103126 and 8312, R-SMAD binding, nuclei, Axin1 and IDBG-154815 and ENSMUSG00000024182 and 12005, AXIN1 and IDBG-633677 and ENSBTAG00000016577 and 504357

Gene info

• Identity
  HGNC:903
• Gene
  AXIN1
• Long gene name
  axin 1
• Synonyms
  • PPP1R49
• Synonyms name
  • protein phosphatase 1, regulatory subunit 49
• GenBank acession
  • AF009674
• Locus
  16p13.3
• Discovery year
  1998-09-17
• Entrez gene record
  8312
• Pubmed identfication
  • 9230313
• Classification
  • Protein phosphatase 1 regulatory subunits
• VEGA ID
  OTTHUMG00000064930

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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