anti-APC5 Antibody

• Catalog number
  5727
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  APC5 Antibody: Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC5 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. While little is known of APC5, it is thought that APC5 associates with other APC/C components APC1, APC4, and CDC23 interdependently, such that loss of any one subunit reduces binding between the remaining three.
• Gene names
  APC5 Antibody: APC5, APC5, Anaphase-promoting complex subunit 5, Cyclosome subunit 5
• Antibodie s label
  unlabelled serum
• Purity
  APC5 Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Antigen
  APC5 antibody was made against a 17 amino acid synthetic peptide near the center of human APC5.
• Immuno application
  ELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
• Antibody advice
  APC5 antibody can be used for detection of APC5 by Western blot at 1 - 2 ug/mL. Antibody can also be used for immunohistochemistry starting at 5 ug/mL. For immunofluorescence start at 20 ug/mL.
• Suspention pH azide
  APC5 Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  APC5 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human, Mouse, Rat
• Omim nr
  37537861
• Ncbi nr
  Q9UJX4
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  51433
• GENE symbol
  ANAPC5
• Antigene name
  anaphase promoting complex subunit 5
• Source
  Homo sapiens
• Protein nr
  Q9UJX4
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  APC5  
• Gene symbol
  ANAPC5
• Short name
  anti-APC5 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toAPC5 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:15713
• Gene
  ANAPC5
• Long gene name
  anaphase promoting complex subunit 5
• Synonyms
  • APC5
• GenBank acession
  • AF191339
• Locus
  12q24.31
• Discovery year
  2001-06-01
• Entrez gene record
  51433
• Pubmed identfication
  • 9469815
• Classification
  • Anaphase promoting complex
• VEGA ID
  OTTHUMG00000169157

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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