Anti-TEAD2 Antibody

• Catalog number
  A1167-100
• Price
  Please ask
• Size
  100 µl

• Antibody Target
  TEAD2
• Target Alternative Name
  TEF4, Transcriptional enhancer factor TEF-4, TEA domain family member 2, TEAD-2
• Antibody Type
  Polyclonal
• Species Reactivities
  Human, Mouse
• Immunogen Sequence
  KLH-conjugated synthetic peptide encompassing a sequence within the center region of human TEAD2
• Accession
  Q15562
• Gene Id
  8463
• Appearance
  Colorless liquid
• Form
  Liquid
• Formulation
  In 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol and 0.01% sodium azide
• Purification
  Affinity purified
• Application
  WB, IH, IF/IC
• Positive Control
  WB: HEK293, RAW264.7, H9C2 cell lysate; IHC: human bresat cancer tissue; IF: HepG2 cells
• Application And Usages
  WB; 1:500 – 1:2000, IHC; 1:50 – 1:200, IF/IC; 1:50 – 1:100, ChIP 1:100 – 1:500
• Description
  Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to the SPH and GT-IIC 'enhansons' (5'-GTGGAATGT-3'). May be involved in the gene regulation of neural development. Binds to the M-CAT motif.
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans
• Handling
  The antibody solution should be gently mixed before use
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Verified
• Immunofluorescence Verified
  Verified
• Immunoprecipitation Verified
  Not Verified
• FACS Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Dot Blot Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Additional description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TEAD2  
• Gene symbol
  TEAD2
• Short name
  Anti-TEAD2 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibody toTEAD2 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:11715
• Gene
  TEAD2
• Long gene name
  TEA domain transcription factor 2
• Synonyms gene name
  • TEA domain family member 2
• Synonyms
  • TEF-4
  • ETF
  • TEF4
• GenBank acession
  • X94440
• Locus
  19q13.33
• Discovery year
  1998-10-09
• Entrez gene record
  8463
• Pubmed identfication
  • 9889009
  • 8702974
• RefSeq identity
  • NM_003598
• Classification
  • TEA domain transcription factors
• VEGA ID
  OTTHUMG00000183174

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

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