anti-Anti-TEAD2 Antibody

anti-Anti-TEAD2 Antibody is available 1 time from Biovision labs

A1167-100 | anti-Anti-TEAD2 Antibodysize: Anti-TEAD2 Antibody | 436.26 USD

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  • Target of this antibody:
    TEAD2
  • Alternative names of antibody target:
    TEF4, Transcriptional enhancer factor TEF-4, TEA domain family member 2, TEAD-2
  • Background information:
    Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to the SPH and GT-IIC 'enhansons' (5'-GTGGAATGT-3'). May be involved in the gene regulation of neural development. Binds to the M-CAT motif.
  • Antibody host:
    Rabbit
  • Clonality of antibody:
    Polyclonal
  • Isotype:
    Rabbit IgG
  • Clone:
    N/A
  • This antibody reacts with:
    Human, Mouse
  • Immunogene sequence:
    KLH-conjugated synthetic peptide encompassing a sequence within the center region of human TEAD2
  • Form of antibody:
    Liquid
  • Formulation of this antibody:
    In 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol and 0.01% sodium azide
  • Purification method:
    Affinity purified
  • This antibody has been succesfully tested for use in following methods:
    WB, IH, IF/IC
  • Recommended usage:
    WB; 1:500 – 1:2000, IHC; 1:50 – 1:200, IF/IC; 1:50 – 1:100, ChIP 1:100 – 1:500
  • Storage information:
    Shelf time: 12 months in temp.: -20 deg.C
  • Shipping conditions:
    gel pack
  • How to handle this antibody:
    The antibody solution should be gently mixed before use
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
  • Properties
    If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
  • Short name
    anti-Anti-TEAD2 Antibody
  • Technique
    Antibody, anti
  • Alternative name
    antibody to-Anti-TEAD2 (Antibody to)
  • Alternative technique
    antibodies
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