Androgen Receptor (AR) Polyclonal Antibody (Human, Rat), HRP

• Catalog number
  PAB252Ra01-20ul-HRP
• Price
  Please ask
• Size
  20ul

• Description
  A Rabbit polyclonal antibody against Human, Rat Androgen Receptor (AR). This antibody is labeled with HRP.
• Specifications
  Host: Rabbit; Species Reactivity: Human, Rat; Clonality: polyclonal; Tested applications: WB, IHC; Concentration: 500ug/ml; Isotype: IgG; Conjugation: HRP
• Additional_information
  Sequence of the immunogen: AR (Val491~Ser679); Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Storage_and_shipping
  Upon receipt, store at -20°C or -80°C. Prepare working aliqotes prior to storage to avoid repeated freeze-thaw cycles.
• Notes
  Research Use Only.
• Properties
  If you buy Antibodies supplied by Cloud Clone Corp they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. HRP conjugates are often primary rabbit polyclonal antibodies couples to the enzyme horseradish peroxidase (HRP), found in the roots of horseradish. Also monoclonal HRP conjugates are often used for Western Blot. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Conjugation
  HRP Conjugated
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera. Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
• Latin name
  Rattus norvegicus
• Additional description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• French translation
  anticorps

• Gene target
  Androgen   Receptor  
• Gene symbol
  ARNILA, AR, ARLNC1
• Short name
  Androgen Receptor (AR) Polyclonal Antibody ( , ),
• Technique
  Polyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Host
  Rat
• Label
  HRP
• Species
  Rat, Humans, Rats
• Alternative name
  Androgen Receptor (AR) polyclonal (antibody to-) (H. sapiens, Rat), horseradish peroxidase
• Alternative technique
  polyclonals, antibodies

Gene info

• Identity
  HGNC:54484
• Gene
  ARNILA
• Long gene name
  androgen receptor negatively regulated lncRNA
• Synonyms name
  • AR negatively induced lncRNA
• Locus
  2p23.3
• Discovery year
  2019-08-14
• Pubmed identfication
  • 29844570
• Classification
  • Long non-coding RNAs with non-systematic symbols

Gene info

• Identity
  HGNC:644
• Gene
  AR
• Long gene name
  androgen receptor
• Synonyms gene
  • DHTR
  • SBMA
• Synonyms gene name
  • dihydrotestosterone receptor
  • spinal and bulbar muscular atrophy
• Synonyms
  • AIS
  • NR3C4
  • SMAX1
  • HUMARA
• Synonyms name
  • testicular feminization
  • Kennedy disease
• GenBank acession
  • M20132
• Locus
  Xq12
• Discovery year
  1986-01-01
• Entrez gene record
  367
• Pubmed identfication
  • 3353726
  • 3377788
• RefSeq identity
  • NM_000044
• Classification
  • Nuclear receptor subfamily 3 group C
• VEGA ID
  OTTHUMG00000021740
• Locus Specific Databases
  • Androgen Receptor
  • Global Variome shared LOVD
  • ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database
  • LRG_1406

Gene info

• Identity
  HGNC:53032
• Gene
  ARLNC1
• Long gene name
  androgen receptor regulated long noncoding RNA 1
• Synonyms gene
  • LINC02170
• Synonyms gene name
  • long intergenic non-protein coding RNA 2170
• Synonyms
  • PRCAT47
• Synonyms name
  • prostate cancer-associated 47
  • AR-regulated long noncoding RNA 1
• Locus
  16q23.2
• Discovery year
  2017-01-09
• Entrez gene record
  100996425
• Pubmed identfication
  • 29808028
• RefSeq identity
  • NR_131947
• Classification
  • Long non-coding RNAs with non-systematic symbols
• VEGA ID
  OTTHUMG00000177012

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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