alpha-Fodrin Antibody

• Catalog number
  3266-30T
• Price
  Please ask
• Size
  30 µg

• Antibody Target
  Fodrin
• Target Alternative Name
  SPTAN1, FLJ44613, SPTA2,
• Antibody Type
  Polyclonal
• Species Reactivities
  Human
• Immunogen Sequence
  Synthetic peptide surrounding amino acid 162 of mouse alpha-Fodrin
• Accession
  P16546
• Gene Id
  20740
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  0.5 mg/ml
• Formulation
  30 µg (0.5 mg/ml) affinity purified rabbit anti-α-Fodrin polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
• Purification
  Affinity purified
• Application
  Western blot, Immunohistochemistry
• Application And Usages
  Western blot analysis (0.5-4 µg/ml) and in in Immunohistochemistry (10-20 µg/ml).
• Description
  Fodrin is a universally expressed membrane-associated cytoskeletal protein consisting of α- and β-subunits. The protein is important for maintaining normal membrane structure and supporting cell surface protein function. α-Fodrin is one of the important targets cleaved by caspases during apoptosis. The full length 240 kDa protein can be cleaved at several sites within its sequence by activated caspases generating N-terminal 150 kDa, C-terminal 120 kDa, and 35 kDa major products. Cleavage of α-Fodrin leads to membrane malfunction and cell shrinkage.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Additional description
  The alpha-Fodrin Antibody is a α- or alpha protein sometimes glycoprotein present in blood.
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  alpha-Fodrin  
• Gene symbol
  SPTAN1
• Short name
  alpha-Fodrin Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  a-Fodrin (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:11273
• Gene
  SPTAN1
• Long gene name
  spectrin alpha, non-erythrocytic 1
• Synonyms name
  • alpha-fodrin
• GenBank acession
  • M19725
• Locus
  9q34.11
• Discovery year
  2001-06-22
• Entrez gene record
  6709
• Pubmed identfication
  • 3336352
• RefSeq identity
  • NM_003127
• Classification
  • EF-hand domain containing
  • Spectrins
• VEGA ID
  OTTHUMG00000020754

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

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