ALDH5A1 Antibody
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Catalog number6750-100
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PricePlease ask
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Size100 μl
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Antibody TargetALDH5A1
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Target Alternative NameALDH5A1; SSADH; Succinate-semialdehyde dehydrogenase, mitochondrial; Aldehyde dehydrogenase family 5 members A1; NAD (+)-dependent succinic semialdehyde dehydrogenase.
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Antibody TypePolyclonal
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Species ReactivitiesHuman.
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Immunogen SequenceThis ALDH5A1 antibody is generated from rabbits immunized with human ALDH5A1 recombinant protein.
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AccessionP51649
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Gene Id7915
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AppearanceColorless liquid
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FormLiquid
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Formulation100 µl of antibody in PBS with 0.09% (W/V) sodium azide
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PurificationThis antibody is purified through a protein A column, followed by peptide affinity purification.
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ApplicationWestern blot, IHC, FACS.
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Positive ControlWestern blot: WiDr cell lysate, IHC: human brain tissue, FACS: WiDr cell lysate.
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Application And UsagesWestern blot: ~1:1000, IHC: ~1:50-1:100, FACS: ~1:10-1:50.
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DescriptionAldehyde dehydrogenases (ALDHs) mediate the NADP+-dependent oxidation of aldehydes into acids and play an important role in the detoxification of alcohol-derived acetaldehyde, as well as in lipid peroxidation and in the metabolism of corticosteroids, biogenic amines and neurotransmitters. ALDH5A1 (aldehyde dehydrogenase 5 family, member A1), also known as SSDH or SSADH, is a 535 amino acid protein that localizes to the mitochondria and belongs to the aldehyde dehydrogenase family. Expressed in a variety of tissues, including liver, heart, lung, brain, kidney and placenta, ALDH5A1 is required for gamma-aminobutyric acid (GABA) recycling from the synaptic cleft. Mutations of ALDH5A1 lead to succinate semialdehyde dehydrogenase deficiency (SSADH deficiency) that is characterized by severe ataxia and by mildly retarded psychomotor development.
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Storage Condition-20 °C
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Shipping Conditiongel pack
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Shelf Life12 months
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UsageFor Research Use Only! Not to be used in humans.
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HandlingThe antibody solution should be gently mixed before use.
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Western Blot VerifiedVerified
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Immunocytochemistry VerifiedVerified
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Immunofluorescence VerifiedNot Verified
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Immunoprecipitation VerifiedNot Verified
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ELISA VerifiedNot Verified
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ChIP VerifiedNot Verified
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Flow Cytometry VerifiedVerified
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PropertiesIf you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolALDH5A1
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Short nameALDH5A1 Antibody
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit IgG
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Alternative nameALDH5A1 (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene namealdehyde dehydrogenase 5 family member A1
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Synonyms gene name
- aldehyde dehydrogenase 5 family, member A1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1999-06-11
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Entrez gene record
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Pubmed identfication
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Classification
- Aldehyde dehydrogenases
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data