Anti-ADRB2 (Ser346) (Polyclonal), ALEXA Fluor 594

• Catalog number
  GENTObs-3002R-A594
• Price
  Please ask
• Size
  100 microliters

• Type
  Conjugated Primary Antibody
• Conjugated with
  ALEXA FLUOR® 594
• Host organism
  Rabbit (Oryctolagus cuniculus)
• Target Protein Peptide
  ADRB2 Ser346
• Specificity
  This antibody reacts specifically with ADRB2 (Ser346)
• Modification
  Phosphorylation
• Modification site
  Ser346
• Clonality
  Polyclonal Antibody
• Clone
  Polyclonal Antibodies
• Concentration
  1ug per 1ul
• Subcellular locations
  Cytoplasm
• Antigen Source
  KLH conjugated synthetic phosphopeptide derived from human ADRB2 around the phosphorylation site of Ser346
• Gene ID
  154
• Swiss Prot
  P07550
• Applications
  IF(IHC-P)
• Applications with corresponding dilutions
  IF(IHC-P)(1:50-200)
• Cross reactive species
  Human (Homo sapiens)
• Cross Reactive Species details
  No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
• Background information
  Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.
• Purification method
  Purified by Protein A.
• Storage
  Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
• Excitation emission
  590nm/617nm
• Synonyms
  BAR; B2AR; ADRBR; ADRB2R; BETA2AR; Beta-2 adrenergic receptor; Beta-2 adrenoreceptor; Beta-2 adrenoceptor; ADRB2
• Also known as
  ADRB2 (Ser346) Polyclonal Antibody
• Other name
  Anti-ADRB2 (Ser346) Polyclonal
• Advisory
  Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
• Properties
  For facs or microscopy Alexa 1 conjugate.
• Conjugation
  Alexa Fluor, ALEXA FLUOR® 594
• Conjugated
  Alexa conjugate 1
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.

• Gene target
  ADRB2   Ser346  
• Gene symbol
  ADRB2
• Short name
  Anti-ADRB2 (Ser346)
• Technique
  Polyclonal, anti-, anti, antibody to, antibodies, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 594
• Alternative name
  ADRB2 (Ser346) Polyclonal Antibody, ALEXA FLUOR® 594 Conjugated
• Alternative technique
  polyclonals, antibodies
• Alternative to gene target
  adrenoceptor beta 2, surface, ADRB2R and ADRBR and B2AR and BAR and BETA2AR, ADRB2 and IDBG-52685 and ENSG00000169252 and 154, norepinephrine binding, nuclei, Adrb2 and IDBG-152615 and ENSMUSG00000045730 and 11555, ADRB2 and IDBG-648668 and ENSBTAG00000002144 and 281605

Gene info

• Identity
  HGNC:286
• Gene
  ADRB2
• Long gene name
  adrenoceptor beta 2
• Synonyms gene
  • ADRB2R
• Synonyms gene name
  • adrenergic, beta-2-, receptor, surface
  • adrenoceptor beta 2, surface
• Synonyms
  • ADRBR
  • BAR
  • B2AR
• GenBank acession
  • AF022953
• Locus
  5q32
• Discovery year
  1990-09-10
• Entrez gene record
  154
• RefSeq identity
  • NM_000024
• Classification
  • Adrenoceptors
• VEGA ID
  OTTHUMG00000129933

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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