GALNT13/GalNAc-T13 Antibody
-
Catalog numberbs-13274R
-
PricePlease ask
-
Size0.1ml
-
-
Long nameGALNT13/GalNAc-T13 Primary Polyclonal Antibody
-
Also known asGALNT13/GalNAc-T13 PAb
-
CategoryPrimary Antibodies
-
ConjugationUnconjugated
-
Target AntigenGALNT13/GalNAc-T13
-
SpecificityThis is a highly specific antibody against GALNT13/GalNAc-T13.
-
Modification sNone
-
Modification site sUnmodified antibody
-
ClonalityPolyclonal antibody
-
Clone numberPolyclonal antibody
-
Concentration1ug per 1ul
-
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GALNT13/GalNAc-T13
-
Gene ID number114805
-
Tested ApplicationsWB, IHC-P, IF(IHC-P)
-
Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
-
Cross reactivityHuman, Mouse, Rat
-
Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
-
Background of the target antigenThe UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes are substrate-specific proteins that catalyze the transfer of GalNAc (N-acetylgalactosamine) to serine and threonine residues onto various proteins, thereby initiating mucin-type O-linked glycosylation in the Golgi apparatus. GalNAc-T13 (Polypeptide N-acetylgalactosaminyltransferase 13), also known as UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 13, is a 556 amino acid protein that displays much stronger enzymatic activity than GalNAc-1 towards GalNAc transfer to mucin peptides such as Muc5a and Muc7. The N-terminal domain is involved in substrate binding and manganese coordination, while the C-terminal domain is involved in UDP-Gal binding and catalytic reaction. With specific expression in the central nervous system, GalNAc-T13 may be responsible for the synthesis of Tn antigen in neuronal cells, which is a universal carcinoma marker on malignant cells.
-
Purification methodThis antibody was purified via Protein A.
-
Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
-
Synonym namesGalNAc T13; GalNAc transferase 13; N acetylgalactosaminyltransferase 13; Polypeptide GalNAc transferase 13; pp GaNTase 13; Protein UDP acetylgalactosaminyltransferase 13; UDP GalNAc:polypeptide N acetylgalactosaminyltransferase 13; UDP N acetyl alpha D galactosamine:polypeptide; GLT13_HUMAN.
-
PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translationanticorps
-
Gene target
-
Gene symbolGALNT13, ANKRD11
-
Short nameAnti-GALNT13/GalNAc-T13
-
TechniqueAntibody, antibodies against human proteins, antibodies for
-
HostRabbit (Oryctolagus cuniculus)
-
IsotypeImmunoglobulin G (IgG)
-
Alternative nameGALNT13/GalNAc-T13 Polyclonal Antibody
-
Alternative techniqueantibodies
-
Gene info
-
Identity
-
Gene
-
Long gene namepolypeptide N-acetylgalactosaminyltransferase 13
-
Synonyms gene name
- UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13 (GalNAc-T13)
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year2003-12-02
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Polypeptide N-acetylgalactosaminyltransferases
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameankyrin repeat domain 11
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2004-01-15
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Ankyrin repeat domain containing
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data