ANGPTL3 Antibody

• Catalog number
  bs-5918R
• Price
  Please ask
• Size
  0.1ml

• Long name
  ANGPTL3 Primary Polyclonal Antibody
• Also known as
  ANGPTL3 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  ANGPTL3
• Specificity
  This is a highly specific antibody against ANGPTL3.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  40-90/460
• Subcellular location
  Secreted
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ANG5/ANGPTL3
• Gene ID number
  27329
• Swiss Prot
  Q9Y5C1
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Angiopoietin-like protein 3 (Angptl3) functions as a potent lipoprotein lipase inhibitor and is an important component of plasma triglyceride homeostasis. Angptl3 also plays a role in adipose formation and angiogenesis through its interaction with integrin ?v)beta(3). It is secreted by the liver and is functionally defined by the C-terminal fibrinogen (FBN)-like domain and an N-terminal coiled-coil domain. Angptl3 regulates circulating triglyceride levels during different nutritional states thereby mediating the feeding/fasting cycle. A deficiency of Angptl3 results in abnormally low lipid levels, and a repression of the protein may be protective against atherosclerosis. Angptl3 may also play an important role in hyperlipidemia in diabetes.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  ANL3; ANG-5; FHBL2; ANGPT5; Angiopoietin-related protein 3; Angiopoietin-5; Angiopoietin-like protein 3; ANGPTL3; UNQ153/PRO179
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  ANGPTL3  
• Gene symbol
  ANGPTL3
• Short name
  Anti-ANGPTL3
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  ANGPTL3 Polyclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  angiopoietin-like 3, ANGPTL3 and IDBG-99367 and ENSG00000132855 and 27329, growth factor activity, Extracellular, Angptl3 and IDBG-166252 and ENSMUSG00000028553 and 30924, ANGPTL3 and IDBG-638594 and ENSBTAG00000021386 and 782603

Gene info

• Identity
  HGNC:491
• Gene
  ANGPTL3
• Long gene name
  angiopoietin like 3
• Synonyms gene
  • ANGPT5
• Synonyms gene name
  • angiopoietin-like 3
• Synonyms name
  • angiopoietin 5
• GenBank acession
  • AF152562
• Locus
  1p31.3
• Discovery year
  2000-02-07
• Entrez gene record
  27329
• Pubmed identfication
  • 10644446
• RefSeq identity
  • NM_014495
• Classification
  • Fibrinogen C domain containing
  • Receptor ligands
  • Angiopoietin like family
• VEGA ID
  OTTHUMG00000009146

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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