Angiopoietin 1 Antibody

• Catalog number
  PA1333-1
• Price
  Please ask
• Size
  0,1 mg

• Target antigen
  Angiopoietin 1
• Clonality
  Polyclonal antibody
• Clone
  Polyclonal antibody
• Raised in
  rabbit
• Type of the antibody
  IgG polyclonal antibody
• Product form
  freeze-dried
• Reacts with species
  human
• Analyses
  WB,IHC-P,ELISA
• Immunogen
  A synthetic peptide corresponding to a sequence in the middle region of human Angiopoietin 1(225-239aa RQTYIIQELEKQLNR), different from the related mouse and rat sequences by two amino acids.
• Product configuration
  Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
• Purification
  Immunogen affinity purified.
• Solubilization
  The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
• Storage condtions
  Keep the Angiopoietin 1 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
• Tips
  The Angiopoietin 1 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
• Background
  Angiopoietin 1 is a type of angiopoietin and is encoded by the gene ANGPT1. Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Angiopoietin-1 seems to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. Endothelial Tie2/Tek ligands angiopoietin-1(ANGPT1) and angiopoietin-2(ANGPT2): regional localization of the human genes to 8q22.3-q23 and 8p23.
• Related articles
  1. "Entrez Gene: ANGPT1 angiopoietin 1". Angiopoietin-1 seems to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. 2. Suri, C., Jones, P. F., Patan, S., Bartunkova, S., Maisonpierre, P. C., Davis, S., Sato, T. N., Yancopoulos, G. D. Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis. Cell 87: 1171-1180, 1996. 3. Cheung, A. H., Stewart, R. J., Marsden, P. A. Endothelial Tie2/Tek ligands angiopoietin-1 (ANGPT1) and angiopoietin-2 (ANGPT2): regional localization of the human genes to 8q22.3-q23 and 8p23. Genomics 48: 389-391, 1998.
• Gene Name
  ANGPT1
• Protein Name
  Angiopoietin-1
• Gene Full Name
  angiopoietin 1
• Synonyms
  AGP 1 antibody|AGP1 antibody|AGPT antibody|ANG 1 antibody|ANG-1 antibody|ANG1 antibody|Angiopoietin-1 antibody|Angiopoietin1 antibody|ANGP1_HUMAN antibody|ANGPT 1 antibody|ANGPT1 antibody|KIAA0003 antibody|OTTHUMP00000227592 antibody|OTTHUMP00000227599 antibody|OTTHUMP00000227600 antibody
• Uniprot ID
  Q15389
• Properties
  If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Angiopoietin  
• Gene symbol
  ANGPTL1, ANGPT1, TEK
• Short name
  Angiopoietin 1 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Alternative name
  Angiopoietin 1 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:489
• Gene
  ANGPTL1
• Long gene name
  angiopoietin like 1
• Synonyms gene
  • ANGPT3
• Synonyms gene name
  • angiopoietin-like 1
• Synonyms
  • ANG3
  • AngY
  • ARP1
• Synonyms name
  • angioarrestin
• GenBank acession
  • AF107253
• Locus
  1q25.2
• Discovery year
  2000-02-07
• Entrez gene record
  9068
• Pubmed identfication
  • 10025962
  • 9286704
• RefSeq identity
  • NM_004673
• Classification
  • Fibrinogen C domain containing
  • Receptor ligands
  • Angiopoietin like family
• VEGA ID
  OTTHUMG00000035075

Gene info

• Identity
  HGNC:484
• Gene
  ANGPT1
• Long gene name
  angiopoietin 1
• Synonyms
  • KIAA0003
  • Ang1
• GenBank acession
  • D13628
• Locus
  8q23.1
• Discovery year
  1997-04-10
• Entrez gene record
  284
• Pubmed identfication
  • 9545648
• RefSeq identity
  • NM_001146
  • NM_139290
• Classification
  • Fibrinogen C domain containing
  • Receptor ligands
• VEGA ID
  OTTHUMG00000164812

Gene info

• Identity
  HGNC:11724
• Gene
  TEK
• Long gene name
  TEK receptor tyrosine kinase
• Synonyms gene
  • VMCM
• Synonyms gene name
  • venous malformations, multiple cutaneous and mucosal
  • TEK tyrosine kinase, endothelial
• Synonyms
  • TIE2
  • TIE-2
  • VMCM1
  • CD202b
• Synonyms name
  • angiopoietin-1 receptor
• GenBank acession
  • L06139
• Locus
  9p21.2
• Discovery year
  1994-05-24
• Entrez gene record
  7010
• Pubmed identfication
  • 1312667
  • 7833915
• Classification
  • Receptor tyrosine kinases
  • Fibronectin type III domain containing
  • CD molecules
  • Immunoglobulin like domain containing
• VEGA ID
  OTTHUMG00000019712

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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