Angiotensin-Converting Enzyme 2 Antibody (ACE2)

• Catalog number
  F49434-0.08ML
• Price
  Please ask
• Size
  0.08 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  Angiotensin-Converting Enzyme 2 (ACE2)
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC, ELISA
• Recommended dilutions
  Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
• Notes
  Titration of the Angiotensin-converting enzyme 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This Angiotensin-converting enzyme 2 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q9BYF1
• Purity
  Purified
• Description
  ACE2 is expressed predominantly in vascular endothelial cells of the heart and kidney. ACE converts angiotensin I to angiotensin II, ACE2 converts angiotensin I to angiotensin 1-9, which has 9 amino acids. Angiotensin II is a potent blood vessel constrictor, while angiotensin 1-9 does not impact blood vessels but is cleaved by ACE to a shorter peptide, angiotensin 1-7, which is a blood vessel dilator.
• Immunogen
  A portion of amino acids 773-805 from the human protein was used as the immunogen for this Angiotensin-converting enzyme 2 antibody.
• Storage
  Aliquot the Angiotensin-converting enzyme 2 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Additional description
  Enzymes are cleaving the substrate. If the substrate is DNA they are called restriction enzymes. Activating enzymes will cut off the domain that is biological active to become functional.
• French translation
  anticorps

• Gene target
  Angiotensin-Converting   ACE2  
• Gene symbol
  ACE2
• Short name
  Anti-Angiotensin-Converting Enzyme 2 (ACE2)
• Technique
  Antibody, Enzyme, antibodies against human proteins, antibodies for, enzymes
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to Angiotensin-Converting Enzyme 2 (ACE2)
• Alternative technique
  antibodies, enzymes
• Alternative to gene target
  angiotensin I converting enzyme (peptidyl-dipeptidase A) 2, ACE2 and IDBG-46534 and ENSG00000130234 and 59272, peptide binding, Extracellular, Ace2 and IDBG-184519 and ENSMUSG00000015405 and 70008, ACE2 and IDBG-638902 and ENSBTAG00000034402 and 101908244,509235

Gene info

• Identity
  HGNC:13557
• Gene
  ACE2
• Long gene name
  angiotensin converting enzyme 2
• Synonyms gene name
  • angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
  • angiotensin I converting enzyme 2
• Synonyms
  • ACEH
• Synonyms name
  • peptidyl-dipeptidase A
• GenBank acession
  • AF291820
• Locus
  Xp22.2
• Discovery year
  2000-09-25
• Entrez gene record
  59272
• Pubmed identfication
  • 10969042
• VEGA ID
  OTTHUMG00000021177
• Locus Specific Databases
  • Global Variome shared LOVD

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products