APC11 Antibody / ANAPC11
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Catalog numberF53960-0.2ML
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PricePlease ask
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Size0.2 ml
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CategoryAntibody
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ConcentrationIn 1X PBS, pH 7.4, with 0.09% sodium azide
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FormAntigen affinity purified
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ConjugationUnconjugated
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ClonePolyclonal antibody
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Recognised antigenAPC11 / ANAPC11
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Host animalRabbit (Oryctolagus cuniculus)
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ClonalityPolyclonal (rabbit origin)
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Species reactivityHuman (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
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Tested applicationsWB
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Recommended dilutionsWestern blot: 1:1000-2000
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Intented useThis APC11 antibodyis to be used only for research purposes and not for diagnostics..
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Gene ID51529
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UniprotQ9NYG5
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PurityAntigen affinity
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DescriptionAnaphase-promoting complex subunit 11, together with the cullin protein ANAPC2, constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex.
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ImmunogenA portion of amino acids 56-94 from the human protein was used as the immunogen for the APC11 antibody.
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StorageAliquot the APC11 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
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PropertiesIf you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolANAPC11
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Short nameAnti- APC11 / ANAPC11
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit Ig
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Alternative nameAntibodies to APC11 / ANAPC11
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameanaphase promoting complex subunit 11
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Synonyms gene name
- anaphase promoting complex subunit 11 (yeast APC11 homolog)
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-03-08
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Anaphase promoting complex
- Ring finger proteins
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data