APP/Amyloid Precursor Protein Antibody, ALEXA FLUOR 350

• Catalog number
  bs-0112R-A350
• Price
  Please ask
• Size
  100ul

• Long name
  APP/Amyloid Precursor Protein Antibody, ALEXA FLUOR 350 Conjugated
• Also known as
  Anti-Amyloid Precursor Protein PAb ALEXA FLUOR 350
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 350
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  Amyloid Precursor Protein
• Specificity
  This is a highly specific antibody against Amyloid Precursor Protein.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  380-430/770
• Subcellular location
  Extracellular
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human of human APP
• Gene ID Number
  351
• Swiss Prot
  P05067
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  343nm/442nm
• Synonyms
  AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; CTFgamma; Amyloid beta A4 protein; APP; Alzheimer disease amyloid protein; Cerebral vascular amyloid peptide; PreA4; Protease nexin-II; A4
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 350
• Description
  Precursor cell, also called a blast cell or simply blast, is a type of partially differentiated, usually unipotent cell that has lost most or all of the stem cell multipotency.
• French translation
  anticorps

• Gene target
  APP/Amyloid   Precursor   Protein  
• Gene symbol
  APP-DT, APP, PABPC4, NAE1
• Short name
  Anti-Amyloid Precursor Protein
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 350
• Alternative name
  APP/Amyloid Precursor Protein Antibody, ALEXA FLUOR 350
• Alternative technique
  antibodies
• Alternative to gene target
  amyloid beta (A4) precursor protein, AAA and ABETA and ABPP and AD1 and APPI and CTFgamma and CVAP and PN-II and PN2, APP and IDBG-1100 and ENSG00000142192 and 351, growth factor receptor binding, nuclei, App and IDBG-172954 and ENSMUSG00000022892 and 11820, APP and IDBG-630293 and ENSBTAG00000017753 and 280722

Gene info

• Identity
  HGNC:55075
• Gene
  APP-DT
• Long gene name
  APP divergent transcript
• Locus
  21q21.3
• Discovery year
  2020-06-12
• Classification
  • Divergent transcripts

Gene info

• Identity
  HGNC:620
• Gene
  APP
• Long gene name
  amyloid beta precursor protein
• Synonyms gene
  • AD1
• Synonyms gene name
  • Alzheimer disease
  • amyloid beta (A4) precursor protein
• Synonyms
  • alpha-sAPP
• Synonyms name
  • peptidase nexin-II
• GenBank acession
  • M15533
• Locus
  21q21.3
• Discovery year
  1986-01-01
• Entrez gene record
  351
• Pubmed identfication
  • 1679289
• RefSeq identity
  • NM_000484
• Classification
  • Receptor ligands
• VEGA ID
  OTTHUMG00000078438
• Locus Specific Databases
  • Alzheimer Disease & Frontotemporal Dementia Mutation Database

Gene info

• Identity
  HGNC:8557
• Gene
  PABPC4
• Long gene name
  poly(A) binding protein cytoplasmic 4
• Synonyms gene name
  • poly(A)-binding protein, cytoplasmic 4 (inducible form)
  • poly(A) binding protein, cytoplasmic 4 (inducible form)
• Synonyms
  • iPABP
  • APP-1
• Synonyms name
  • activated-platelet protein 1
  • Inducible poly(A)-binding protein
• GenBank acession
  • U33818
• Locus
  1p34.3
• Discovery year
  1999-12-17
• Entrez gene record
  8761
• Pubmed identfication
  • 10543404
• RefSeq identity
  • NM_001135653
• Classification
  • RNA binding motif containing
  • Small nucleolar RNA protein coding host genes
• VEGA ID
  OTTHUMG00000009097

Gene info

• Identity
  HGNC:621
• Gene
  NAE1
• Long gene name
  NEDD8 activating enzyme E1 subunit 1
• Synonyms gene
  • APPBP1
• Synonyms gene name
  • amyloid beta precursor protein binding protein 1, 59kDa
• Synonyms
  • ula-1
  • APP-BP1
• GenBank acession
  • U50939
• Locus
  16q22.1
• Discovery year
  1999-01-13
• Entrez gene record
  8883
• Pubmed identfication
  • 8626687
  • 12740388
• RefSeq identity
  • NM_003905
• Classification
  • Ubiquitin like modifier activating enzymes
• VEGA ID
  OTTHUMG00000137513

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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