Amyloid beta Precusor Protein Antibody (APP)

  • Catalog number
    F49577-0.08ML
  • Price
    Please ask
  • Size
    0.08 ml
  • Category
    Antibody
  • Concentration
    In 1X PBS, pH 7.4, with 0.09% sodium azide
  • Form
    Purified
  • Conjugation
    Unconjugated
  • Clone
    Polyclonal antibody
  • Recognised antigen
    Amyloid beta Precusor Protein (APP)
  • Host animal
    Rabbit (Oryctolagus cuniculus)
  • Clonality
    Polyclonal (rabbit origin)
  • Species reactivity
    Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
  • Tested applications
    WB, ELISA
  • Recommended dilutions
    Western blot: 1:1000
  • Notes
    Titration of the Amyloid beta antibody may be required due to differences in protocols and secondary/substrate sensitivity.
  • Intented use
    This Amyloid beta antibodyis to be used only for research purposes and not for diagnostics..
  • Uniprot
    P05067
  • Purity
    Purified
  • Description
    APP is a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Aβ is the main component of amyloid plaques (extracellular deposits found in the brains of patients with Alzheimer's disease).[19] Similar plaques appear in some variants of Lewy body dementia and in inclusion body myositis (a muscle disease), while Aβ can also form the aggregates that coat cerebral blood vessels in cerebral amyloid angiopathy. [Wiki]
  • Immunogen
    A portion of amino acids 736-770 from the human protein was used as the immunogen for this Amyloid beta antibody.
  • Storage
    Aliquot the Amyloid beta antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
  • Properties
    If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    Amyloid   beta   Precusor   Protein   APP  
  • Gene symbol
    APP-DT, APP, PABPC4, NAE1
  • Short name
    Anti-Amyloid beta Precusor Protein (APP)
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Isotype
    Rabbit Ig
  • Alternative name
    Antibodies to Amyloid beta Precusor Protein (APP)
  • Alternative technique
    antibodies
  • Alternative to gene target
    amyloid beta (A4) precursor protein, AAA and ABETA and ABPP and AD1 and APPI and CTFgamma and CVAP and PN-II and PN2, APP and IDBG-1100 and ENSG00000142192 and 351, growth factor receptor binding, nuclei, App and IDBG-172954 and ENSMUSG00000022892 and 11820, APP and IDBG-630293 and ENSBTAG00000017753 and 280722
Gene info
  • Identity
  • Gene
  • Long gene name
    APP divergent transcript
  • Locus
  • Discovery year
    2020-06-12
  • Classification
    • Divergent transcripts
Gene info
Gene info
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Similar products
Filters
Contact
Chat with gentaur.com employee