Amlodipine, L-type Ca channel blocker
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Catalog number
SIH-315-250MG
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Price
Please ask
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Size
250 mg
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Stock availabilitIn Stock
In Stock
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CAS number
111470-99-6
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Description
L-type Ca channel blocker
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Molecular weight
567,05 g/mol
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Primary research fields
Neuroscience, Ion Channels, Calcium Channels, Voltage-Gated Calcium Channels
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Other name
3-Ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydro-3,5-pyridinedicarboxylate, Norvasc
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Product category
Small Molecules
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Product type
Inhibitor
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Chemical formula
C20H25ClN2O5•C6H5SO3H
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Origin
Synthetic
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Purity pourcentage
>98%
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Soluble in
Soluble to 100 mM in DMSO and to 10 mM in water
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Physical appearance
White Solid
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Storage recommendations
-20ºC
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Shipping recommendations
Shipped Ambient
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Safety information
Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Risk Phrases: R22 - Harmful if swallowed R62 - Possible risk of impaired fertility Hazard Phrases: H302-H315-H319-H335 Precautionary Phrases: P261-P305 + P351 + P338
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PubChem number
2162
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Scientific context
Amlodipine is a long-acting calcium channel blocker used as an anti-hypertensive and in the treatment of angina. It acts by relaxing the smooth muscle in the arterial wall, decreasing total peripheral resistance and hence reducing blood pressure.
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Bibliography
1. Luksa J., Josic D., Kremser M., Kopitar Z and Milutinovic S. (1997) J Chromatorgraphy. B, Biomed Sci and App. 693(2): 367-375. 2. Bahl V.K., Jadhav U.M., Thacker H.P. (2009) Am J Cardiovasc Drugs. 9(3): 135-142.
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Release date
8-Apr-2011
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PubMed number
Refer to PubMed
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Tested applications
To be tested
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Tested reactivity
To be tested
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Representative figure legend
Chemical structure of Amlodipine (SIH-315), a L-type Ca channel blocker. CAS #: 111470-99-6. Molecular Formula: C20H25ClN2O5 · C6H5SO3H . Molecular Weight: 567.05 g/mol. Chemical structure of Amlodipine, a L-type Ca channel blocker (SIH-315). CAS # 111470-99-6. Molecular Formula: C20H25ClN2O5 · C6H5SO3H .
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Warning information
Non-hazardous
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Country of production
Canada
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Total weight kg
0.25
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Net weight g
0.25
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Gene target
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Short name
Amlodipine, L- Ca channel blocker
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Alternative name
Amlodipine, L-classification Ca channel blocker
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