Amlodipine, L-type Ca channel blocker

  • Catalog number
    SIH-315-250MG
  • Price
    Please ask
  • Size
    250 mg
  • Stock availabilitIn Stock
    In Stock
  • CAS number
    111470-99-6
  • Description
    L-type Ca channel blocker
  • Molecular weight
    567,05 g/mol
  • Primary research fields
    Neuroscience, Ion Channels, Calcium Channels, Voltage-Gated Calcium Channels
  • Other name
    3-Ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydro-3,5-pyridinedicarboxylate, Norvasc
  • Product category
    Small Molecules
  • Product type
    Inhibitor
  • Chemical formula
    C20H25ClN2O5•C6H5SO3H
  • Origin
    Synthetic
  • Purity pourcentage
    >98%
  • Soluble in
    Soluble to 100 mM in DMSO and to 10 mM in water
  • Physical appearance
    White Solid
  • Storage recommendations
    -20ºC
  • Shipping recommendations
    Shipped Ambient
  • Safety information
    Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Risk Phrases: R22 - Harmful if swallowed R62 - Possible risk of impaired fertility Hazard Phrases: H302-H315-H319-H335 Precautionary Phrases: P261-P305 + P351 + P338
  • PubChem number
    2162
  • Scientific context
    Amlodipine is a long-acting calcium channel blocker used as an anti-hypertensive and in the treatment of angina. It acts by relaxing the smooth muscle in the arterial wall, decreasing total peripheral resistance and hence reducing blood pressure.
  • Bibliography
    1. Luksa J., Josic D., Kremser M., Kopitar Z and Milutinovic S. (1997) J Chromatorgraphy. B, Biomed Sci and App. 693(2): 367-375. 2. Bahl V.K., Jadhav U.M., Thacker H.P. (2009) Am J Cardiovasc Drugs. 9(3): 135-142.
  • Release date
    8-Apr-2011
  • PubMed number
    Refer to PubMed
  • Tested applications
    To be tested
  • Tested reactivity
    To be tested
  • Representative figure legend
    Chemical structure of Amlodipine (SIH-315), a L-type Ca channel blocker. CAS #: 111470-99-6. Molecular Formula: C20H25ClN2O5 · C6H5SO3H . Molecular Weight: 567.05 g/mol. Chemical structure of Amlodipine, a L-type Ca channel blocker (SIH-315). CAS # 111470-99-6. Molecular Formula: C20H25ClN2O5 · C6H5SO3H .
  • Warning information
    Non-hazardous
  • Country of production
    Canada
  • Total weight kg
    0.25
  • Net weight g
    0.25
  • Gene target
  • Short name
    Amlodipine, L- Ca channel blocker
  • Alternative name
    Amlodipine, L-classification Ca channel blocker
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