Amgen IRE1α Inhibitor
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Catalog numberA576530
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PricePlease ask
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Size1 mg
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Chemical available in other sizesPlease inquire size and price
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Stock availabilityPlease Inquire
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Cas number1630086-20-2
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Chemical s molecular weight601.12
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Chemical s main applicationsAmgen IRE1α Inhibitor is an inhibitor of IRE1α. IRE1α is a sensor of unfolded protein accumulation that triggers the unfolded protein response.
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Chemical s categoryAromatics, Inhibitors, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
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Other name(S)-2-Chloro-N-(6-methyl-5-((3-(2-(piperidin-3-ylamino)pyrimidin-4-yl)pyridin-2-yl)oxy)naphthalen-1-yl)benzenesulfonamide
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Chemical s formulaC31H29ClN6O3S
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Physical propertiesNo Data Available
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Melting temperatureNo Data Available
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Boiling temperatureNo Data Available
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Chemical s soluble inNo Data Available
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Stability conditionsNo Data Available
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StorageNo Data Available
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DescriptionTissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
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Gene target
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Gene symbolERN1
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Short nameAmgen IRE1α Inhibitor
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Alternative nameAmgen IRE1α suppressor
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Gene info
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Identity
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Gene
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Long gene nameendoplasmic reticulum to nucleus signaling 1
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Synonyms gene name
- ER to nucleus signalling 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1998-08-06
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Endoribonucleases
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VEGA ID