Alpha 1 Antitrypsin Antibody / AAT / SERPINA1

• Catalog number
  R32565
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  Alpha 1 Antitrypsin / AAT / SERPINA1
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB
• Recommended dilutions
  Western blot: 0.5-1ug/ml
• Added buffer
  Lyophilized from 1X Phosphate Buffered Saline (PBS) with 2.5% BSA and 0.025% sodium azide
• Intented use
  This AAT antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P01009
• Purity
  Antigen affinity
• Description
  SERPINA1 is also known as PI, A1A or AAT. This gene is mapped to 14q32.1. The protein encoded by this gene is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this gene.
• Immunogen
  Amino acids E25-T204 from the human protein were used as the immunogen for the AAT antibody.
• Storage
  After reconstitution, the AAT antibody may be kept for up to one month refrigerated at +4 degrees C.For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Additional description
  The Anti- Alpha 1 Antitrypsin / AAT / SERPINA1 is a α- or alpha protein sometimes glycoprotein present in blood.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Alpha   Antitrypsin   AAT   SERPINA1  
• Gene symbol
  SERPINA1, TRI-AAT1-1, TRI-AAT7-1, TRI-AAT4-1, TRI-AAT3-1, TRI-AAT11-1, TRI-AAT7-2, TRI-AAT12-1, TRI-AAT6-1, TRI-AAT8-1
• Short name
  Anti- Alpha 1 Antitrypsin / AAT / SERPINA1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to Alpha 1 Antitrypsin / AAT / SERPINA1
• Alternative technique
  antibodies
• Alternative to gene target
  serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1, A1A and A1AT and AAT and alpha1AT and PI and PI1 and PRO2275, SERPINA1 and IDBG-18174 and ENSG00000197249 and 5265, identical protein binding, Extracellular, Serpina1f and IDBG-167371 and ENSMUSG00000021081 and 68348, SERPINA1 and IDBG-634001 and ENSBTAG00000018843 and 280699

Gene info

• Identity
  HGNC:8941
• Gene
  SERPINA1
• Long gene name
  serpin family A member 1
• Synonyms gene
  • PI
• Synonyms gene name
  • serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
• Synonyms
  • AAT
  • A1A
  • PI1
  • alpha-1-antitrypsin
  • A1AT
  • alpha1AT
• Synonyms name
  • protease inhibitor 1
  • anti-elastase
  • alpha-1 antitrypsin
  • alpha-1 proteinase inhibitor
• GenBank acession
  • X01683
• Locus
  14q32.13
• Discovery year
  1986-01-01
• Entrez gene record
  5265
• Pubmed identfication
  • 24172014
• RefSeq identity
  • NM_001002235
• Classification
  • Serpin peptidase inhibitors
• VEGA ID
  OTTHUMG00000150355
• Locus Specific Databases
  • LRG_575

Gene info

• Identity
  HGNC:34812
• Gene
  TRI-AAT1-1
• Long gene name
  tRNA-Ile (anticodon AAT) 1-1
• Synonyms gene
  • TRNAI12
• Synonyms gene name
  • transfer RNA isoleucine 12 (anticodon AAU)
  • transfer RNA-Ile (AAT) 1-1
• Synonyms
  • tRNA-Ile-AAT-1-1
• GenBank acession
  • HG983843
• Locus
  6p11.2
• Discovery year
  2008-08-29
• Entrez gene record
  100189249
• Classification
  • Cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:34710
• Gene
  TRI-AAT7-1
• Long gene name
  tRNA-Ile (anticodon AAT) 7-1
• Synonyms gene
  • TRNAI8
• Synonyms gene name
  • transfer RNA isoleucine 8 (anticodon AAU)
  • transfer RNA-Ile (AAT) 7-1
• Synonyms
  • tRNA-Ile-AAT-7-1
• GenBank acession
  • HG983853
• Locus
  6p22.2
• Discovery year
  2008-08-29
• Entrez gene record
  100189401
• Classification
  • Cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:34961
• Gene
  TRI-AAT4-1
• Long gene name
  tRNA-Ile (anticodon AAT) 4-1
• Synonyms gene
  • TRNAI24
• Synonyms gene name
  • transfer RNA isoleucine 24 (anticodon AAU)
  • transfer RNA-Ile (AAT) 4-1
• Synonyms
  • tRNA-Ile-AAT-4-1
• GenBank acession
  • HG983846
• Locus
  17p13.1
• Discovery year
  2008-08-29
• Entrez gene record
  100189393
• Classification
  • Cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:34776
• Gene
  TRI-AAT3-1
• Long gene name
  tRNA-Ile (anticodon AAT) 3-1
• Synonyms gene
  • TRNAI11
• Synonyms gene name
  • transfer RNA isoleucine 11 (anticodon AAU)
  • transfer RNA-Ile (AAT) 3-1
• Synonyms
  • tRNA-Ile-AAT-3-1
• GenBank acession
  • HG983845
• Locus
  6p22.1
• Discovery year
  2008-08-29
• Entrez gene record
  100189213
• Classification
  • Cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:35047
• Gene
  TRI-AAT11-1
• Long gene name
  tRNA-Ile (anticodon AAT) 11-1
• Synonyms gene
  • TRNAI29P
• Synonyms gene name
  • transfer RNA isoleucine 29 (anticodon AAU) pseudogene
  • transfer RNA-Ile (AAT) 11-1
• Synonyms
  • tRNA-Ile-AAT-11-1
• GenBank acession
  • HG983858
• Locus
  12q24.33
• Discovery year
  2008-08-29
• Entrez gene record
  100189474
• RefSeq identity
  • NG_008532
• Classification
  • Cytoplasmic transfer RNA pseudogenes

Gene info

• Identity
  HGNC:34970
• Gene
  TRI-AAT7-2
• Long gene name
  tRNA-Ile (anticodon AAT) 7-2
• Synonyms gene
  • TRNAI25
• Synonyms gene name
  • transfer RNA isoleucine 25 (anticodon AAU)
  • transfer RNA-Ile (AAT) 7-2
• Synonyms
  • tRNA-Ile-AAT-7-2
• GenBank acession
  • HG983854
• Locus
  6p22.2
• Discovery year
  2008-08-29
• Entrez gene record
  107986683
• Classification
  • Cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:35054
• Gene
  TRI-AAT12-1
• Long gene name
  tRNA-Ile (anticodon AAT) 12-1
• Synonyms gene
  • TRNAI30P
• Synonyms gene name
  • transfer RNA isoleucine 30 (anticodon AAU) pseudogene
  • transfer RNA-Ile (AAT) 12-1
• Synonyms
  • tRNA-Ile-AAT-12-1
• GenBank acession
  • HG983859
• Locus
  20q13.2
• Discovery year
  2008-08-29
• Entrez gene record
  100189481
• Classification
  • Cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:34940
• Gene
  TRI-AAT6-1
• Long gene name
  tRNA-Ile (anticodon AAT) 6-1
• Synonyms gene
  • TRNAI22
• Synonyms gene name
  • transfer RNA isoleucine 22 (anticodon AAU)
  • transfer RNA-Ile (AAT) 6-1
• Synonyms
  • tRNA-Ile-AAT-6-1
• GenBank acession
  • HG983852
• Locus
  6p22.2
• Discovery year
  2008-08-29
• Entrez gene record
  100189372
• Classification
  • Cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:34656
• Gene
  TRI-AAT8-1
• Long gene name
  tRNA-Ile (anticodon AAT) 8-1
• Synonyms gene
  • TRNAI5
• Synonyms gene name
  • transfer RNA isoleucine 5 (anticodon AAU)
  • transfer RNA-Ile (AAT) 8-1
• Synonyms
  • tRNA-Ile-AAT-8-1
• GenBank acession
  • HG983855
• Locus
  6p22.1
• Discovery year
  2008-08-29
• Entrez gene record
  100189095
• Classification
  • Cytoplasmic transfer RNAs

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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