ALDH1A3 Antibody

• Catalog number
  A03030
• Price
  Please ask
• Size
  0,1 mg

• Target antigen
  ALDH1A3
• Clonality
  Polyclonal antibody
• Clone
  Polyclonal antibody
• Raised in
  rabbit
• Type of the antibody
  IgG polyclonal antibody
• Product form
  freeze-dried
• Reacts with species
  human, mouse, rat
• Analyses
  WB,IHC-P
• Immunogen
  E.coli-derived human ALDH1A3 recombinant protein (Position: N37-K154). Human ALDH1A3 shares 89% and 87.3% amino acid (aa) sequence identity with mouse and rat ALDH1A3, respectively.
• Product configuration
  Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
• Purification
  Immunogen affinity purified.
• Solubilization
  The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
• Storage condtions
  Keep the ALDH1A3 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
• Tips
  The ALDH1A3 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
• Background
  Aldehyde dehydrogenase 1 family, member A3, also known as ALDH1A3 or retinaldehyde dehydrogenase 3 (RALDH3), is an enzyme that in humans is encoded by the ALDH1A3 gene. Aldehyde dehydrogenase isozymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The enzyme encoded by this gene uses retinal as a substrate, either in a free or a cellular retinol-binding protein form. Mutations in this gene have been associated with microphthalmia, isolated 8, and expression changes have also been detected in tumor cells. Alternative splicing results in multiple transcript variants.
• Related articles
  1. Nishimura M, Yoshitsugu H, Naito S, Hiraoka I (2002). "Evaluation of gene induction of drug-metabolizing enzymes and transporters in primary culture of human hepatocytes using high-sensitivity real-time reverse transcription PCR.". Yakugaku Zasshi. 122 (5): 339–61. 2. Rexer BN, Zheng WL, Ong DE (2001). "Retinoic acid biosynthesis by normal human breast epithelium is via aldehyde dehydrogenase 6, absent in MCF-7 cells.". Cancer Res. 61 (19): 7065–70. 3. Yoshida A, Rzhetsky A, Hsu LC, Chang C (1998). "Human aldehyde dehydrogenase gene family.". Eur. J. Biochem. 251 (3): 549–57.
• Gene Name
  ALDH1A3
• Protein Name
  Aldehyde dehydrogenase family 1 member A3
• Gene Full Name
  aldehyde dehydrogenase 1 family member A3
• Synonyms
  Aldh1a3 | ALDH1A6 | ALDH6 | RALDH 3 | V1 | P47895
• Uniprot ID
  P47895
• Entrez GeneID
  220
• Properties
  If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  ALDH1A3  
• Gene symbol
  ALDH1A3-AS1, ALDH1A3
• Short name
  ALDH1A3 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Alternative name
  aldehyde dehydrogenase 1 family, member A3 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  aldehyde dehydrogenase 1 family, member A3, ALDH1A6 and ALDH6 and MCOP8 and RALDH3, ALDH1A3 and IDBG-32178 and ENSG00000184254 and 220, oxidoreductase activity, Cytoplasm, Aldh1a3 and IDBG-191846 and ENSMUSG00000015134 and 56847, ALDH1A3 and IDBG-628582 and ENSBTAG00000009125 and 507093,534200

Gene info

• Identity
  HGNC:55416
• Gene
  ALDH1A3-AS1
• Long gene name
  ALDH1A3 antisense RNA 1
• Locus
  15q26.3
• Discovery year
  2021-01-06
• Entrez gene record
  101927751
• RefSeq identity
  • NR_135827
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:409
• Gene
  ALDH1A3
• Long gene name
  aldehyde dehydrogenase 1 family member A3
• Synonyms gene
  • ALDH6
• Synonyms gene name
  • aldehyde dehydrogenase 1 family, member A3
• Synonyms
  • RALDH3
• Synonyms name
  • retinaldehyde dehydrogenase 3
• GenBank acession
  • U07919
• Locus
  15q26.3
• Discovery year
  1994-07-07
• Entrez gene record
  220
• Pubmed identfication
  • 7698756
• RefSeq identity
  • NM_000693
• Classification
  • Aldehyde dehydrogenases
• VEGA ID
  OTTHUMG00000186439

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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