ALDH1A2 Antibody
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Catalog numberbs-12460R
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PricePlease ask
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Size0.1ml
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Long nameALDH1A2 Primary Polyclonal Antibody
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Also known asALDH1A2 PAb
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CategoryPrimary Antibodies
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ConjugationUnconjugated
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Target AntigenALDH1A2
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SpecificityThis is a highly specific antibody against ALDH1A2.
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Modification sNone
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Modification site sUnmodified antibody
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ClonalityPolyclonal antibody
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Clone numberPolyclonal antibody
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Concentration1ug per 1ul
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SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ALDH1A2
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Gene ID number8854
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Tested ApplicationsWB, IHC-P, IF(IHC-P)
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Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigenAldehyde dehydrogenases (ALDHs) mediate NADP+-dependent oxidation of aldehydes into acids during the detoxification of alcohol-derived acetaldehyde; metabolism of corticosteroids, biogenic amines and neurotransmitters; and lipid peroxidation. ALDH1A1, also designated retinal dehydrogenase 1 (RalDH1 or RALDH1), aldehyde dehydrogenase family 1 member A1, aldehyde dehydrogenase cytosolic, ALDHII, ALDH-E1 or ALDH E1, is a retinal dehydrogenase that participates in the biosynthesis of retinoic acid (RA). There are two major liver isoforms of ALDH1 that can localize to cytosolic or mitochondrial space. The ALDH1A2 (RALDH2, RALDH2-T) gene produces three different transcripts and also catalyzes the synthesis of RA from retinaldehyde. ALDH1A3 (ALDH6, RALDH3, ALDH1A6) is a 37 kb gene that consists of 13 exons and produces a major transcript of approximately 3.5 kb most abundant in salivary gland, stomach and kidney. ALDH3A1 (stomach type, ALDH3, ALDHIII) forms a cytoplasmic homodimer that preferentially oxidizes aromatic aldehyde substrates. ALDH genes upregulate as a part of the oxidative stress response, and appear to be abundant in certain tumors that have an accelerated metabolism toward chemotherapy agents.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym namesL1A2_HUMAN; Aldehyde dehydrogenase family 1 member A2; ALDH1A2 aldehyde dehydrogenase 1 family, member A2; ALDH1A2; Aldh1a7; AV116159; MGC26444; RALDH 2; RALDHII; Raldh1; RalDH2; RALDH2 T; Retinal dehydrogenase 2; Retinaldehyde dehydrogenase 2; Retinaldehyde specic dehydrogenase type 2; Retinaldehyde-specic dehydrogenase type 2.
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PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolALDH1A2, ALDH1A2-AS1
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Short nameAnti-ALDH1A2
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TechniqueAntibody, antibodies against human proteins, antibodies for
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HostRabbit (Oryctolagus cuniculus)
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IsotypeImmunoglobulin G (IgG)
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Alternative nameALDH1A2 Polyclonal Antibody
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Alternative techniqueantibodies
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Alternative to gene targetaldehyde dehydrogenase 1 family, member A2, RALDH(II) and RALDH2 and RALDH2-T, ALDH1A2 and IDBG-13982 and ENSG00000128918 and 101928635,8854, oxidoreductase activity, Cytoplasm, Aldh1a2 and IDBG-182855 and ENSMUSG00000013584 and 19378, ALDH1A2 and IDBG-646601 and ENSBTAG00000010119 and 535075
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Gene info
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Identity
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Gene
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Long gene namealdehyde dehydrogenase 1 family member A2
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Synonyms gene name
- aldehyde dehydrogenase 1 family, member A2
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2001-03-30
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Entrez gene record
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Pubmed identfication
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Classification
- Aldehyde dehydrogenases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameALDH1A2 antisense RNA 1
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Locus
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Discovery year2021-01-07
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Entrez gene record
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RefSeq identity
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Classification
- Antisense RNAs
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data