Akt, alpha serine/threonine-protein kinase

• Catalog number
  AS16 4007
• Price
  Please ask
• Size
  100 µg

• Available ordering format
  Liquid
• Immunogen
  Recombinant human Interleukin 10 and P3X63-AG8.653 myeloma cells. UniProt: P31749
• Raised in
  Mouse
• Clonality
  Monoclonal
• Clone
  9Q7, IgG3
• Purification
  Affinity purified.
• How to reconstitute
  See included datasheet or contact our support service
• Storage condition
  Store at -20°C.
• Verified applications
  Western Blot (WB)
• Connected products
  anti-mouse secondary antibodies
• Recommended dilutions for use
  Optimal concentrations should be determined by serial dilutions.
• Molecular weight expected аpparent
  see datasheet
• Verified reactivity
  Human, Mouse, Rat
• Possible reactivity
  to be determined
• No reactivity
  No confirmed exceptions from predicted reactivity known at the moment.
• Supplementary information
  Contact Gentaur support center at [email protected]
• References
  To be added when available, antibody released in November 2016.
• Scientific context
  Akt is a serine/threonine kinase that plays an important role in many biological processes like metabolism, cell survival and growth. Akt is activated by the protein PI3K, which then interact with other cytoskeletal proteins. AKT/PKB is active in various types of cancer, and by promoting cell invasiveness and angiogenesis it contributes to tumor progression.
• Notes
  Provided as sterile filtered solution in phosphate buffered saline pH 7.2.
• Protein number
  P31749
• TAIR number
  Refer to NCBI
• Hyperlink
• Description
  The Akt, alpha serine/threonine-protein kinase is a α- or alpha protein sometimes glycoprotein present in blood. Serine protease, D- or L-serine arginine rich enzyme of serine threonine kinase with serine that is encoded by the codons UCU, UCC, UCA, UCG, AGU and AGC is an ɑ-amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated −NH+ 3 form under biological conditions), a carboxyl group. It is non-essential in humans, meaning the body can synthesize it.

• Gene target
  Akt   alpha   serine/threonine-protein   kinase  
• Gene symbol
  AKT1
• Short name
  Akt, alpha serine/threonine-protein kinase
• Alternative name
  Akt, a serine/threonine-protein phosphorylation catalyst

Gene info

• Identity
  HGNC:391
• Gene
  AKT1
• Long gene name
  AKT serine/threonine kinase 1
• Synonyms gene name
  • v-akt murine thymoma viral oncogene homolog 1
• Synonyms
  • RAC
  • PKB
  • PRKBA
  • AKT
  • RAC-alpha
• Synonyms name
  • protein kinase B
• GenBank acession
  • M63167
• Locus
  14q32.33
• Discovery year
  1986-01-01
• Entrez gene record
  207
• Pubmed identfication
  • 21214427
• RefSeq identity
  • NM_005163
• Classification
  • Pleckstrin homology domain containing
  • AKT kinases
• VEGA ID
  OTTHUMG00000170795
• Locus Specific Databases
  • LRG_721

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