RIP Antibody
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Catalog numberR31162
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PricePlease ask
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Size0.1mg
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CategoryAntibody
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Concentration0.5mg/ml if reconstituted with 0.2ml sterile DI water
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FormAntigen affinity purified
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ConjugationUnconjugated
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ClonePolyclonal antibody
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Recognised antigenRIP
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Host animalRabbit (Oryctolagus cuniculus)
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ClonalityPolyclonal (rabbit origin)
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Species reactivityHuman (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
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Tested applicationsWB
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Recommended dilutionsWestern blot: 0.5-1ug/ml
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NotesThe stated application concentrations are suggested starting amounts. Titration of the RIP antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Intented useThis RIP antibodyis to be used only for research purposes and not for diagnostics..
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UniprotQ13546
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PurityAntigen affinity
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DescriptionReceptor-interacting serine/threonine-protein kinase 1 (RIPK1), also called RIP, is an enzyme that in humans is encoded by the RIPK1 gene. Members of the TRAF protein family have been implicated in the activation of NF-kappa-B by the TNF superfamily. By yeast 2-hybrid and coimmunoprecipitation studies using mammalian cell extracts, Hsu et al.(1996) showed that RIP interacts with TRADD, TRAF1, TRAF2, and TRAF3. Hartz(2012) mapped the RIPK1 gene to chromosome 6p25.2 based on an alignment of the RIP sequence with the genomic sequence. Stanger et al.(1995) found that overexpression of Rip in mammalian cells induced morphologic changes characteristic of apoptosis. They suggested that RIP may be an important element in the signal transduction machinery that mediates programmed cell death.
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ImmunogenAn amino acid sequence from the middle region of human Receptor-interacting serine/threonine-protein kinase 1 (RRRRVSHDPFAQQRP) was used as the immunogen for this RIP antibody.
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StorageAfter reconstitution, the RIP antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
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PropertiesIf you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolRIPK1, AGFG1, RPAIN, KRR1, RALBP1, MPRIP
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Short nameAnti-RIP
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit IgG
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Alternative nameAntibodies to RIP
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene namereceptor interacting serine/threonine kinase 1
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Synonyms gene name
- receptor (TNFRSF)-interacting serine-threonine kinase 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1999-05-07
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Ripoptosome
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameArfGAP with FG repeats 1
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Synonyms gene
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Synonyms gene name
- HIV-1 Rev binding protein
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Synonyms
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Locus
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Discovery year1996-11-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- ArfGAPs
- MicroRNA protein coding host genes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameRPA interacting protein
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Synonyms
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GenBank acession
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Locus
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Discovery year2006-05-08
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameKRR1 small subunit processome component homolog
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Synonyms gene
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Synonyms gene name
- HIV-1 rev binding protein 2
- KRR1, small subunit (SSU) processome component, homolog (yeast)
- KRR1, small subunit processome component homolog
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-12-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- SSU processome
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameralA binding protein 1
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-02-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemyosin phosphatase Rho interacting protein
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2008-06-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Pleckstrin homology domain containing
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
