AG1296,PDGFR kinase inhibitor
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Catalog numberSIH-426-25MG
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PricePlease ask
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Size25 mg
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Research Area sCell Signaling , Cancer , Apoptosis , Cancer Growth Inhibitors , Tyrosine Kinase Inhibitors
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CategorySmall Molecules
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Product TypeInhibitor
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CAS No146535-11-7
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MolecularFormulaC16H14N2O2
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Molecular Weight266.3
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Purity≥98% (TLC)
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SolubilitySoluble in DMSO or dichloromethane
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AppearanceOff-white to brownish solid
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Storage Temperature-20°C
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Shipping TemperatureShipped Ambient
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DescriptionTissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
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Gene target
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Gene symbolPDGFRB
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Short nameAG1296 PDGFR kinase inhibitor
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Alternative nameAG1296,PDGFR phosphorylation catalyst suppressor
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Gene info
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Identity
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Gene
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Long gene nameplatelet derived growth factor receptor beta
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Synonyms gene
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Synonyms gene name
- platelet-derived growth factor receptor, beta polypeptide
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-06-22
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Entrez gene record
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RefSeq identity
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Classification
- Receptor tyrosine kinases
- CD molecules
- I-set domain containing
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VEGA ID