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Products_type
Antibody
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Products_short_name
[SMAD6]
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Products_name_syn
[Anti-SMAD6 Antibody (aa85-99) IHC-plus; SMAD6; AOVD2; HSMAD6; HsT17432; SMAD 6; MADH7; Mothers against DPP homolog 6; SMAD family member 6; MAD homolog 6; MADH6; Human SMAD6]
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Other_names
[mothers against decapentaplegic homolog 6; Mothers against decapentaplegic homolog 6; mothers against decapentaplegic homolog 6; MAD homolog 6; SMAD, mothers against DPP homolog 6; mothers against decapentaplegic, drosophila, homolog of, 6; SMAD family member 6; SMAD family member 6; SMAD 6; Smad6; hSMAD6]
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Products_gene_name
[SMAD6]
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Other_gene_names
[SMAD6; SMAD6; AOVD2; MADH6; MADH7; HsT17432; MADH6; MAD homolog 6; Mothers against DPP homolog 6; SMAD 6; Smad6; hSMAD6]
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Clonality
Polyclonal
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Reactivity
Human, Pig Predicted Reactivity: Bovine, Dog (at least 90% immunogen sequence identity)
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Specificity
Synthetic peptides corresponding to amino acids 85-99 (RAGGPPRPMSEPGAG) and amino acids 372-388 (NLEQRSESVRRTRSKIG) of human SMAD6 (GenBank Accession No. AAH12986.1). These peptide sequences are specific to SMAD6, and have high homology to SMAD6in multiple species.
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Purity
Protein G Purified
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Form
PBS, 0.05% BSA, 0.05% sodium azide.
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Concentration
0.5 mg/ml
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Storage_stability
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles.
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Tested_application
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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About
Immunoglobulin gamma, IgG, mouse monoclonal H&L chain clones or rabbit, goat polyclonal antibodies have 4 parts. There are 2 heavy chains, 2 light chains. The IgG antibody has 2 antigen binding sites. They represent 70% or more of serum antibodies. This antibody can be antigen purified or protein A or G purified. For storage sodium azide is added or you can call us to request azide free antibody preparations. These will need colder storage temperatures. Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera. Rabbits are used for polyclonal antibody production by MyBioSource. Rabbit antibodies are very stable and can be stored for several days at room temperature. MyBioSource adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Group
Polyclonals and antibodies
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Latin name
Oryctolagus cuniculus
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Gene target
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Gene symbol
SMAD6
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Short name
Rabbit Polyclonal (IgG) SMAD6
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Technique
Polyclonal, Rabbit, IgG, IgGs, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
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Host
Rabbit, Rabbits
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Isotype
IgG, IgG
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Species
Human, Humans
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Alternative name
production species: rabbit polyclonal (Immunoglobulin G) to H. sapiens SMAD family member 6
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Alternative technique
polyclonals, rabbit-anti, immunoglobulins
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Alternative to gene target
SMAD family member 6, AOVD2 and HsT17432 and MADH6 and MADH7, SMAD6 and IDBG-18304 and ENSG00000137834 and 4091, transforming growth factor beta receptor, nuclei, Smad6 and IDBG-175757 and ENSMUSG00000036867 and 17130, SMAD6 and IDBG-645465 and ENSBTAG00000000625 and 511279
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