Active Interleukin 6 Receptor (IL6R)

• Catalog number
  APB815Mu02
• Price
  Please ask
• Size
  10ug

• Source
  NA
• Predicted Molecular Mass KD
  18.0kDa
• Accurate Molecular Mass KD
  18kDa
• Organism species
  Mus musculus (Mouse)
• Item Name
  Interleukin 6 Receptor
• Alternative Names
  CD126; gp80; IL6R; IL-6R-1; IL-6R-Alpha; IL6RA; IL-6 receptor subunit alpha; Membrane glycoprotein 80
• Research Area
  Signal transduction;CD & Adhesion molecule;Infection immunity;
• Buffer Formulation
  PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Traits
  Freeze-dried powder
• Isoelectric Point
  6.5
• Purity
  > 97%
• Protein length
  Ala52~Ala204
• Tag
  N-terminal His Tag
• Expression System
  NA
• Application
  Cell culture; Activity Assays.
• Manual link
• Description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  Active   Interleukin   Receptor   IL6R  
• Gene symbol
  IL6R-AS1, IL6R
• Short name
  Active Interleukin 6 Receptor (IL6R)
• Host
  NA
• Species
  Mus musculus (Mouse)
• Alternative name
  functionnal Interleukin 6 Receptor (interleukin 6 receptor)
• Alternative to gene target
  interleukin 6 receptor, CD126 and gp80 and IL-6R-1 and IL-6RA and IL6Q and IL6RA and IL6RQ, IL6R and IDBG-102945 and ENSG00000160712 and 3570, ciliary neurotrophic factor binding, Extracellular, Il6ra and IDBG-165233 and ENSMUSG00000027947 and 16194, BT.68623 and IDBG-632509 and ENSBTAG00000018474 and 507359

Gene info

• Identity
  HGNC:53716
• Gene
  IL6R-AS1
• Long gene name
  IL6R antisense RNA 1
• Synonyms
  • RP11-350G8.5
• Locus
  1q21.3
• Discovery year
  2017-08-30
• Pubmed identfication
  • 28839111
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:6019
• Gene
  IL6R
• Long gene name
  interleukin 6 receptor
• Synonyms
  • CD126
  • IL-6R
  • IL-1Ra
  • IL6RA
  • gp80
• Synonyms name
  • membrane glycoprotein 80
  • interleukin 6 receptor subunit alpha
• GenBank acession
  • X12830
• Locus
  1q21.3
• Discovery year
  2001-06-22
• Entrez gene record
  3570
• Pubmed identfication
  • 8428753
  • 12633863
• RefSeq identity
  • NM_000565
• Classification
  • CD molecules
  • Interleukin receptors
  • Immunoglobulin like domain containing
• VEGA ID
  OTTHUMG00000036073

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